Colloidal Graphite-Assisted Laser Desorption/Ionization Mass Spectrometry and MSn of Small Molecules. 1. Imaging of Cerebrosides Directly from Rat Brain Tissue

Graphite-assisted laser desorption/ionization (GALDI) mass spectrometry (MS) was investigated for analysis of cerebrosides in a complex total brain lipid extract. Conventional MALDI MS and GALDI MS were compared regarding lipid analysis by using high-vacuum (HV,

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Bibliographic Details
Published in:Analytical chemistry (Washington) 2007-03, Vol.79 (6), p.2373-2385
Main Authors: CHA, Sangwon, YEUNG, Edward S.
Format: Article
Language:English
Subjects:
Animals
Brain
Colloids
Graphite - chemistry
Lipids - chemistry
Microscopy, Electron, Scanning
Rats
Tandem Mass Spectrometry - methods
Online Access:Get full text
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Description
Summary:Graphite-assisted laser desorption/ionization (GALDI) mass spectrometry (MS) was investigated for analysis of cerebrosides in a complex total brain lipid extract. Conventional MALDI MS and GALDI MS were compared regarding lipid analysis by using high-vacuum (HV,
ISSN:0003-2700
1520-6882
DOI:10.1021/ac062251h