Bell's expression and the generalized Garg form for forced dissociation of a biomolecular complex

The dissociation of a biomolecular complex under the action of constant force, constant loading rate, and periodic force is studied theoretically. We show that the celebrated Bell expression provides a good approximation for the bond dissociation rate when F/F(c)

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Bibliographic Details
Published in:Physical review letters 2007-02, Vol.98 (8), p.088304-088304, Article 088304
Main Authors: Lin, Han-Jou, Chen, Hsuan-Yi, Sheng, Yu-Jane, Tsao, Heng-Kwong
Format: Article
Language:English
Subjects:
Computer Simulation
Macromolecular Substances - chemistry
Models, Chemical
Protein Binding
Thermodynamics
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Summary:The dissociation of a biomolecular complex under the action of constant force, constant loading rate, and periodic force is studied theoretically. We show that the celebrated Bell expression provides a good approximation for the bond dissociation rate when F/F(c)
ISSN:0031-9007
1079-7114
DOI:10.1103/PhysRevLett.98.088304