Bell's expression and the generalized Garg form for forced dissociation of a biomolecular complex

The dissociation of a biomolecular complex under the action of constant force, constant loading rate, and periodic force is studied theoretically. We show that the celebrated Bell expression provides a good approximation for the bond dissociation rate when F/F(c)

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Published in:Physical review letters 2007-02, Vol.98 (8), p.088304-088304, Article 088304
Main Authors: Lin, Han-Jou, Chen, Hsuan-Yi, Sheng, Yu-Jane, Tsao, Heng-Kwong
Format: Article
Language:English
Subjects:
Computer Simulation
Macromolecular Substances - chemistry
Models, Chemical
Protein Binding
Thermodynamics
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container_title Physical review letters
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creator Lin, Han-Jou
Chen, Hsuan-Yi
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description The dissociation of a biomolecular complex under the action of constant force, constant loading rate, and periodic force is studied theoretically. We show that the celebrated Bell expression provides a good approximation for the bond dissociation rate when F/F(c)
doi_str_mv 10.1103/PhysRevLett.98.088304
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subjects Computer Simulation
Macromolecular Substances - chemistry
Models, Chemical
Protein Binding
Thermodynamics
title Bell's expression and the generalized Garg form for forced dissociation of a biomolecular complex
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