Assessment of sensory neuropathy in diabetic patients without diabetic foot problems

Abstract Objectives To study the incidence and extent of peripheral sensory neuropathy in diabetic patients without diabetic foot problems (DFPs) with 10 years duration of diabetes using three different modalities of testing: Pin-Prick Testing, 5.07 Semmes-Weinstein Monofilament Testing (SWMT) and R...

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Bibliographic Details
Published in:Journal of diabetes and its complications 2008-03, Vol.22 (2), p.126-131
Main Authors: Nather, Aziz, Neo, Shu Hui, Chionh, Siok Bee, Liew, Stanley C.F, Sim, Eileen Y, Chew, Jocelyn L.L
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Diabetes
Diabetic Foot - diagnosis
Diabetic Foot - physiopathology
Diabetic Neuropathies - diagnosis
Diabetic Neuropathies - physiopathology
Endocrinology & Metabolism
Ethnic Groups
Feet
Female
Foot
Foot diseases
Humans
Male
Middle Aged
Monofilament
Mortality
Neurometer
Neurons, Afferent - physiology
Neuropathy
Pain
Pin-Prick
Singapore
Stress, Mechanical
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Summary:Abstract Objectives To study the incidence and extent of peripheral sensory neuropathy in diabetic patients without diabetic foot problems (DFPs) with 10 years duration of diabetes using three different modalities of testing: Pin-Prick Testing, 5.07 Semmes-Weinstein Monofilament Testing (SWMT) and Rapid-Current Perception Threshold (R-CPT) measurements using the Neurometer. Methods Our study population consisted of 60 patients (120 feet) treated for diabetes mellitus in the Division of Endocrinology at the National University Hospital. No patient had any DFPs. Twenty-two, 21 and 17 patients had duration of diabetes of 10 years, respectively. All patients were tested for sensory neuropathy using Pin-Prick Testing using a standardized protocol, SWMT and the Neurometer. Results There was a significantly higher incidence of sensory neuropathy detected by both the Pin-Prick Test and the Neurometer as compared to the SWMT. Also, in all three modalities, there was a significant increase in incidence of sensory neuropathy detected in diabetics with >5 years duration of diabetes. In addition, the Pin-Prick Test showed an increase in extent of sensory neuropathy with a longer duration of diabetes. Conclusions The Pin-Prick Test was found to be a simple, cheap and useful diagnostic tool for detection of sensory neuropathy in diabetics without DFPs. In addition, it could accurately delineate the extent of neuropathy in the lower limb — additional useful information not obtainable with SWMT or Neurometer. Even for patients with
ISSN:1056-8727
1873-460X
DOI:10.1016/j.jdiacomp.2006.10.007