Persistence of Legionella in hospital water supplies and nosocomial Legionnaires' disease

The molecular epidemiology of clinical and environmental Legionella species isolates was studied in seven hospitals from 1989 to 2006. The number of environmental pulsed field gel electrophoresis (PFGE) patterns ranged from one to nine according to the hospital. Genomic PFGE pattern persistence was...

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Bibliographic Details
Published in:FEMS immunology and medical microbiology 2008-03, Vol.52 (2), p.202-206
Main Authors: Garcia-Nuñez, Marian, Sopena, Nieves, Ragull, Sonia, Pedro-Botet, Maria Luisa, Morera, Josep, Sabria, Miguel
Format: Article
Language:English
Subjects:
Clinical isolates
Cluster Analysis
Cross Infection - epidemiology
DNA Fingerprinting
DNA, Bacterial - genetics
Drinking water
Electrophoresis
Electrophoresis, Gel, Pulsed-Field
Epidemiology
Gel electrophoresis
Genotype
hospital-acquired Legionnaires' disease
Hospitals
Humans
Legionella
Legionella pneumophila - classification
Legionella pneumophila - isolation & purification
Legionnaire's disease
Legionnaires' disease
Legionnaires' Disease - epidemiology
Legionnaires' disease bacterium
Molecular Epidemiology
Nosocomial infection
persistence
PFGE typing
Water Microbiology
Water Supply
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Summary:The molecular epidemiology of clinical and environmental Legionella species isolates was studied in seven hospitals from 1989 to 2006. The number of environmental pulsed field gel electrophoresis (PFGE) patterns ranged from one to nine according to the hospital. Genomic PFGE pattern persistence was observed in 71% of the hospitals, even after 17 years in some hospitals, and the relationship between environmental and clinical isolates was established. The isolates associated with hospital-acquired Legionnaires' disease corresponded to the persistent environmental PFGE patterns of Legionella pneumophila in potable water supplies.
ISSN:0928-8244
1574-695X
2049-632X
DOI:10.1111/j.1574-695X.2007.00362.x