Germ Cells Are Forever

Germ cells are the only cell type capable of generating an entirely new organism. In order to execute germline-specific functions and to retain the capacity for totipotency, germ cells repress somatic differentiation, interact with a specialized microenvironment, and use germline-specific networks o...

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Bibliographic Details
Published in:Cell 2008-02, Vol.132 (4), p.559-562
Main Authors: Cinalli, Ryan M., Rangan, Prashanth, Lehmann, Ruth
Format: Article
Language:English
Subjects:
Animals
Gene Expression Regulation
Germ Cells - cytology
Germ Cells - metabolism
RNA Interference
Transcription, Genetic
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Summary:Germ cells are the only cell type capable of generating an entirely new organism. In order to execute germline-specific functions and to retain the capacity for totipotency, germ cells repress somatic differentiation, interact with a specialized microenvironment, and use germline-specific networks of RNA regulation.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2008.02.003