Effects of a combined aerobic and resistance exercise program in breast cancer survivors: a randomized controlled trial

Few randomized controlled trials have examined the effects of combined aerobic and resistance training in breast cancer survivors soon after completing adjuvant therapy. Breast cancer survivors ( N  = 58) within 2 years of completing adjuvant therapy were randomly assigned to an immediate exercise g...

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Bibliographic Details
Published in:Breast cancer research and treatment 2008-03, Vol.108 (2), p.279-288
Main Authors: Milne, Helen M., Wallman, Karen E., Gordon, Sandy, Courneya, Kerry S.
Format: Article
Language:English
Subjects:
Adult
Aged
Anxiety - prevention & control
Biological and medical sciences
Body Image
Breast cancer
Breast Neoplasms - physiopathology
Breast Neoplasms - psychology
Breast Neoplasms - therapy
Cancer research
Cancer therapies
Clinical outcomes
Clinical Study
Clinical trials
Cross-Over Studies
Exercise
Exercise Therapy
Fatigue - prevention & control
Female
Gynecology. Andrology. Obstetrics
Humans
Mammary gland diseases
Medical sciences
Medicine
Medicine & Public Health
Middle Aged
Muscle Strength
Oncology
Patient Compliance
Physical Fitness
Prospective Studies
Quality of Life
Surveys and Questionnaires
Survivor
Survivors
Time Factors
Treatment Outcome
Tumors
Weightlifting
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Summary:Few randomized controlled trials have examined the effects of combined aerobic and resistance training in breast cancer survivors soon after completing adjuvant therapy. Breast cancer survivors ( N  = 58) within 2 years of completing adjuvant therapy were randomly assigned to an immediate exercise group (IEG; n  = 29) or a delayed exercise group (DEG; n  = 29). The IEG completed 12 weeks of supervised aerobic and resistance exercise, three times per week. The DEG completed the program during the next 12 weeks. Participants completed patient-rated outcomes at baseline, 6, 12, 18 and 24 weeks. The primary endpoint was overall quality of life (QoL) measured by the Functional Assessment of Cancer Therapy-Breast scale. Secondary endpoints were fatigue, social physique anxiety, and physical fitness. Follow-up data was obtained on 97% of participants and exercise adherence was 61.3%. Repeated measures analyses of variance revealed a significant group by time interaction for overall QoL ( P  
ISSN:0167-6806
1573-7217
DOI:10.1007/s10549-007-9602-z