Restless Legs Syndrome is Associated with DSM-IV Major Depressive Disorder and Panic Disorder in the Community

The authors examined the association between restless legs syndrome (RLS) and DSM-IV major depressive disorder and panic disorder based on Wave III and IV of the Baltimore ECA follow-up study. Of 1071 participants, 1024 completed the RLS Questionnaire and Diagnostic Interview Schedule. Adjusted odds...

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Bibliographic Details
Published in:The journal of neuropsychiatry and clinical neurosciences 2008-01, Vol.20 (1), p.101-105
Main Authors: Lee, Hochang B, Hening, Wayne A, Allen, Richard P, Kalaydjian, Amanda E, Earley, Christopher J, Eaton, William W, Lyketsos, Constantine G
Format: Article
Language:English
Subjects:
Adult and adolescent clinical studies
Aged
Anxiety disorders. Neuroses
Biological and medical sciences
Comorbidity
Cross-Sectional Studies
Depression
Depressive Disorder, Major - epidemiology
Diagnostic and Statistical Manual of Mental Disorders
Female
Humans
Male
Medical sciences
Middle Aged
Mood disorders
Nervous system (semeiology, syndromes)
Nervous system as a whole
Neurology
Odds Ratio
Panic disorder
Panic Disorder - epidemiology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Residence Characteristics
Restless Legs Syndrome - epidemiology
Surveys and Questionnaires
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Summary:The authors examined the association between restless legs syndrome (RLS) and DSM-IV major depressive disorder and panic disorder based on Wave III and IV of the Baltimore ECA follow-up study. Of 1071 participants, 1024 completed the RLS Questionnaire and Diagnostic Interview Schedule. Adjusted odds ratio for diagnosis of major depressive disorder (4.7, 95% confidence interval [1.6, 14.5]) and panic disorder (12.9 [3.6, 46.0]) and comorbidity of major depressive disorder and panic disorder (9.7 [1.4, 69.0]) in the past 12 months suggested a strong association between restless legs syndrome and major depressive disorder and/or panic disorder.
ISSN:0895-0172
1545-7222
DOI:10.1176/jnp.2008.20.1.101