A novel method for determining residence time distribution in intricately structured microreactors

A precise characterisation of microreactors can be achieved by determining the residence time distribution as one of the most important flow characteristics. An approach specially designed for microreactor applications was developed, which employs a tracer 'injection' using the optical act...

Full description

Saved in:
Bibliographic Details
Published in:Lab on a chip 2008-01, Vol.8 (3), p.431-438
Main Authors: Lohse, Sebastian, Kohnen, Boris Terje, Janasek, Dirk, Dittrich, Petra Stephanie, Franzke, Joachim, Agar, David William
Format: Article
Language:English
Subjects:
Equipment and Supplies
Fluorescent Dyes
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A precise characterisation of microreactors can be achieved by determining the residence time distribution as one of the most important flow characteristics. An approach specially designed for microreactor applications was developed, which employs a tracer 'injection' using the optical activation of a caged fluorescent dye. Furthermore, the effect of the laminar flow on the determination of the residence time distribution in microreactors has been taken into account during the measurements and their interpretation to fulfill the requirements of the so-called 'mixing-cup-problem' on the microscale. Residence time distributions for an intricately structured thin microreactor were determined for different velocities. The ideality of the stimulus signal generated by the newly introduced technique is demonstrated for an analytically well-defined straight channel and compared with a signal derived from deconvolution of non-ideal input signals.
ISSN:1473-0197
1473-0189
DOI:10.1039/b714190d