Prostate-Specific Antigen Levels, Prostate-Specific Antigen Kinetics, and Prostate Cancer Prognosis: A Tocsin Calling for Prospective Studies

Fall et al show the challenges with using PSA measures to identify tumors that meet the ultimate definition of "biologic aggressiveness," causing the death of the patient. It must be recognized, however, that the patients in this series were substantially different from the majority of pat...

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 2007-04, Vol.99 (7), p.496-497
Main Authors: Parekh, Dipen J., Ankerst, Donna P., Thompson, Ian M.
Format: Article
Language:English
Subjects:
Health risk assessment
Humans
Incidence
Kinetics
Male
Oncology
Predictive Value of Tests
Prognosis
Prospective Studies
Prostate cancer
Prostate-Specific Antigen - metabolism
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - epidemiology
Reproducibility of Results
United States - epidemiology
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Summary:Fall et al show the challenges with using PSA measures to identify tumors that meet the ultimate definition of "biologic aggressiveness," causing the death of the patient. It must be recognized, however, that the patients in this series were substantially different from the majority of patients with localized prostate cancer today in countries where PSA screening is highly prevalent (such as the United States).
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/djk129