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Impaired glucose regulation, elevated glycated haemoglobin and cardiac ischaemic events in vascular surgery patients

Aims  Cardiac morbidity and mortality is high in patients undergoing high‐risk surgery. This study investigated whether impaired glucose regulation and elevated glycated haemoglobin (HbA1c) levels are associated with increased cardiac ischaemic events in vascular surgery patients. Methods  Baseline...

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Published in:Diabetic medicine 2008-03, Vol.25 (3), p.314-319
Main Authors: Feringa, H. H. H., Vidakovic, R., Karagiannis, S. E., Dunkelgrun, M., Elhendy, A., Boersma, E., Van Sambeek, M. R. H. M., Noordzij, P. G., Bax, J. J., Poldermans, D.
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Language:English
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Summary:Aims  Cardiac morbidity and mortality is high in patients undergoing high‐risk surgery. This study investigated whether impaired glucose regulation and elevated glycated haemoglobin (HbA1c) levels are associated with increased cardiac ischaemic events in vascular surgery patients. Methods  Baseline glucose and HbA1c were measured in 401 vascular surgery patients. Glucose  7.0% (n = 63, 16%) were at 2.8‐fold, 2.1‐fold, 5.3‐fold and 5.6‐fold increased risk for ischaemia, troponin release, 30‐day and long‐term cardiac events, respectively. Conclusions  Impaired glucose regulation and elevated HbA1c are risk factors for cardiac ischaemic events in vascular surgery patients.
ISSN:0742-3071
1464-5491
DOI:10.1111/j.1464-5491.2007.02352.x