The Effect of Isolated Left Bundle Branch Block on the Myocardial Velocities and Myocardial Performance Index

Objectives: This study was planned in order to investigate the effect of left bundle branch block (LBBB) on myocardial velocities obtained by tissue Doppler echocardiography (TDE) and myocardial performance index (MPI). Methods: Subjects with LBBB (n = 61) and age‐matched healthy subjects (n = 60) w...

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Bibliographic Details
Published in:Echocardiography (Mount Kisco, N.Y.) N.Y.), 2008-03, Vol.25 (3), p.256-263
Main Authors: Akif Duzenli, Mehmet, Ozdemir, Kurtulus, Soylu, Ahmet, Aygul, Nazif, Yazici, Mehmet, Tokac, Mehmet
Format: Article
Language:English
Subjects:
Blood Flow Velocity
Bundle-Branch Block - diagnostic imaging
Bundle-Branch Block - physiopathology
cardiac function
Echocardiography, Doppler
Female
Humans
left bundle branch block
Male
Middle Aged
Myocardial Contraction
myocardial performance index
myocardial velocity
Stroke Volume
tissue Doppler echocardiography
Ventricular Function, Left
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Summary:Objectives: This study was planned in order to investigate the effect of left bundle branch block (LBBB) on myocardial velocities obtained by tissue Doppler echocardiography (TDE) and myocardial performance index (MPI). Methods: Subjects with LBBB (n = 61) and age‐matched healthy subjects (n = 60) were enrolled in the study. Left ventricular (LV) ejection fraction (EF), mitral inflow velocities (E‐wave and A‐wave), isovolumetric contraction and relaxation time (ICT and IRT), ejection time (ET), and flow propagation velocity (Vp) were measured by conventional echocardiography. Systolic velocity (Sm), early and late diastolic velocities (Em and Am) and time intervals were measured by TDE. MPI was calculated by the formula (ICT + IRT)/ET. Results: LVEF and mitral E/A ratio were similar in both groups. Vp was lower in the LBBB group than in the control group, whereas the E/Em and the E/Vp ratio was higher. LV Sm and Em/Am ratio were lower in LBBB group. Right ventricular Sm and Em/Am ratio were similar in both groups. LV mean and RV MPI were significantly increased in LBBB group. Conclusion: These findings obtained by TDE show that isolated LBBB impairs the ventricular functions. Both of the LV and RV dysfunctions shown by the new parameters may contribute to increased morbidity and mortality in cases with isolated LBBB.
ISSN:0742-2822
1540-8175
DOI:10.1111/j.1540-8175.2007.00579.x