Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging

Abstract Purpose The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. Materials and methods Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign...

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Bibliographic Details
Published in:Clinical imaging 2008-03, Vol.32 (2), p.121-127
Main Authors: Li, Chao-Shiang, Huang, Guo-Shu, Wu, Hong-Da, Chen, Wei-Tsung, Shih, Li-Sun, Lii, Jiunn-Ming, Duh, Shyi-Jye, Chen, Ran-Chou, Tu, Hsing-Yang, Chan, Wing P
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Contrast Media
Diagnosis, Differential
Fascicular sign
Female
Gadolinium DTPA
Humans
Investigative techniques, diagnostic techniques (general aspects)
Magnetic resonance (MR) imaging
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
Nerve Sheath Neoplasms - diagnosis
Neurilemmoma - diagnosis
Neurofibroma - diagnosis
Neurology
Peripheral nerve sheath tumor
Peripheral Nervous System Neoplasms - diagnosis
Radiology
Split fat sign
Target sign
Tumors of the nervous system. Phacomatoses
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Summary:Abstract Purpose The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. Materials and methods Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign (schwannoma, n =16; neurofibroma, n =1) or malignant ( n =9) PNST were retrospectively reviewed. The size, location, shape, margin, and signal intensities of the tumors on precontrast and gadolinium-enhanced MR imaging were analyzed. In each patient, the presence or absence of split fat, target, and fascicular signs was determined. Results The mean size of the benign PNSTs (3.4 cm, S.D.=2.5 cm) was significantly smaller than that of the malignant tumors (8.2 cm, S.D.=3.1 cm) ( P
ISSN:0899-7071
1873-4499
DOI:10.1016/j.clinimag.2007.05.006