Phenome connections

Human phenomics is about to come of age with studies that systematically assess the overlap and relationships among all human genetic diseases. A recent study by Andrey Rzhetsky and colleagues illustrates the power of phenomics by revealing links between conditions that were thought to be distinct,...

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Bibliographic Details
Published in:Trends in genetics 2008-03, Vol.24 (3), p.103-106
Main Authors: Oti, Martin, Huynen, Martijn A, Brunner, Han G
Format: Article
Language:English
Subjects:
Biological and medical sciences
Classical genetics, quantitative genetics, hybrids
Fundamental and applied biological sciences. Psychology
Genetic Diseases, Inborn - genetics
Genetic Testing
Genetic Variation
Genetics of eukaryotes. Biological and molecular evolution
Genomics
Genotype
Human
Humans
Medical Education
Molecular and cellular biology
Phenotype
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Summary:Human phenomics is about to come of age with studies that systematically assess the overlap and relationships among all human genetic diseases. A recent study by Andrey Rzhetsky and colleagues illustrates the power of phenomics by revealing links between conditions that were thought to be distinct, suggesting that they share a genetic basis. Their results imply that the human phenome can be viewed as a landscape of interrelated diseases, reflecting overlapping molecular causation.
ISSN:0168-9525
DOI:10.1016/j.tig.2007.12.005