Matrix-assisted pulsed laser evaporation of poly(D,L-lactide) for biomedical applications: effect of near infrared radiation

The deposition of thin films of poly(D,L-lactide) (PDLLA) by using the matrix-assisted pulsed laser evaporation (MAPLE) technique is investigated. PDLLA is a highly biocompatible and biodegradable polymer, with wide applicability in the biomedical field. The laser wavelength used in the MAPLE proces...

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Bibliographic Details
Published in:Journal of Biomedical Optics 2008-01, Vol.13 (1), p.014028-014026
Main Authors: Califano, Valeria, Bloisi, Francesco, Vicari, Luciano R. M, Bretcanu, Oana, Boccaccini, Aldo R
Format: Article
Language:English
Subjects:
biopolymers
Coated Materials, Biocompatible - chemistry
Coated Materials, Biocompatible - radiation effects
coatings
Crystallization - methods
Damage
Deposition
Evaporation
Fourier transforms
Gases - chemistry
Gases - radiation effects
Infrared Rays
Infrared spectroscopy
Lasers
Materials Testing
matrix-assisted pulsed laser evaporation
poly(D,L-lactide)
Polyesters - chemistry
Polyesters - radiation effects
Pulsed lasers
thin films
Wavelengths
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Summary:The deposition of thin films of poly(D,L-lactide) (PDLLA) by using the matrix-assisted pulsed laser evaporation (MAPLE) technique is investigated. PDLLA is a highly biocompatible and biodegradable polymer, with wide applicability in the biomedical field. The laser wavelength used in the MAPLE process is optimized to obtain a good-quality deposition. The structure of the polymer film is analyzed by Fourier transform infrared spectroscopy (FTIR). It is found that the chemical structure of PDLLA undergoes little or no damage during deposition with near-infrared laser radiation . It is thus confirmed that at this wavelength, the MAPLE technique can be applied for fragile biopolymer molecules, which are easily damaged by other laser radiations (UV radiation). This method allows future development of tailored polymer coatings for biomedical applications.
ISSN:1083-3668
1560-2281
DOI:10.1117/1.2830660