Selective Fluorescent Detection of Flavin Adenine Dinucleotide in Human Eosinophils by Using Bis(Zn2+-Dipicolylamine) Complex

A novel fluorescent sensor based on the Zn2+-DPA complex shows selective detection of flavin adenine dinucleotide (FAD) from among other flavins in water, and it was used to detect FAD in eosinophils by fluorescence microscopy and FACS.

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Bibliographic Details
Published in:Journal of the American Chemical Society 2007-04, Vol.129 (15), p.4524-4525
Main Authors: Rhee, Hyun-Woo, Choi, Ha-Young, Han, Kyungja, Hong, Jong-In
Format: Article
Language:English
Subjects:
Amines - chemistry
Eosinophils - chemistry
Flavin-Adenine Dinucleotide - analysis
Flavin-Adenine Dinucleotide - chemistry
Humans
Molecular Structure
Picolinic Acids - chemistry
Spectrometry, Fluorescence
Zinc - chemistry
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Description
Summary:A novel fluorescent sensor based on the Zn2+-DPA complex shows selective detection of flavin adenine dinucleotide (FAD) from among other flavins in water, and it was used to detect FAD in eosinophils by fluorescence microscopy and FACS.
ISSN:0002-7863
1520-5126
DOI:10.1021/ja070026r