Synthesis of enantiomerically pure isotopomers of 2-phenylpropionic acids

A series of enantiomerically pure [D,13C]‐labeled isotopomeric 2‐phenylpropionic acids were efficiently synthesized using a diastereoselective alkylation and kinetic resolution strategy. Chirality, 2007. © 2007 Wiley‐Liss, Inc.

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Bibliographic Details
Published in:Chirality (New York, N.Y.) N.Y.), 2007-05, Vol.19 (5), p.366-373
Main Authors: Chavda, Sameer, Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Flinn, Anthony, Ghilagaber, Stephanos, Northen, Julian, Yohannes, Yonas
Format: Article
Language:English
Subjects:
2-phenylpropionic acid
alkylation
chiral
diastereoselective
evans
isotopomers
kinetic resolution
oxazolidinones
profens
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Summary:A series of enantiomerically pure [D,13C]‐labeled isotopomeric 2‐phenylpropionic acids were efficiently synthesized using a diastereoselective alkylation and kinetic resolution strategy. Chirality, 2007. © 2007 Wiley‐Liss, Inc.
ISSN:0899-0042
1520-636X
DOI:10.1002/chir.20384