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Polarizability of G4-DNA Observed by Electrostatic Force Microscopy Measurements
G4-DNA, a quadruple helical motif of stacked guanine tetrads, is stiffer and more resistant to surface forces than double-stranded DNA (dsDNA), yet it enables self-assembly. Therefore, it is more likely to enable charge transport upon deposition on hard supports. We report clear evidence of polariza...
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| Published in: | Nano letters 2007-04, Vol.7 (4), p.981-986 |
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| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-a409t-d326217865284ddae28b952dcf9f8fd212a21226609c8602e819c5f0bcc9b25e3 |
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| cites | cdi_FETCH-LOGICAL-a409t-d326217865284ddae28b952dcf9f8fd212a21226609c8602e819c5f0bcc9b25e3 |
| container_end_page | 986 |
| container_issue | 4 |
| container_start_page | 981 |
| container_title | Nano letters |
| container_volume | 7 |
| creator | Cohen, Hezy Sapir, Tomer Borovok, Natalia Molotsky, Tatiana Di Felice, Rosa Kotlyar, Alexander B Porath, Danny |
| description | G4-DNA, a quadruple helical motif of stacked guanine tetrads, is stiffer and more resistant to surface forces than double-stranded DNA (dsDNA), yet it enables self-assembly. Therefore, it is more likely to enable charge transport upon deposition on hard supports. We report clear evidence of polarizability of long G4-DNA molecules measured by electrostatic force microscopy, while coadsorbed dsDNA molecules on mica are electrically silent. This is another sign that G4-DNA is potentially better than dsDNA as a conducting molecular wire. |
| doi_str_mv | 10.1021/nl070013b |
| format | article |
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| fulltext | fulltext |
| identifier | ISSN: 1530-6984 |
| ispartof | Nano letters, 2007-04, Vol.7 (4), p.981-986 |
| issn | 1530-6984 1530-6992 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70370778 |
| source | American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list) |
| subjects | Analytical, structural and metabolic biochemistry Anisotropy Biological and medical sciences Cross-disciplinary physics: materials science rheology DNA - chemistry Electric Conductivity Exact sciences and technology Fundamental and applied biological sciences. Psychology G-Quadruplexes General aspects, investigation methods Materials science Methods of nanofabrication Microscopy, Atomic Force - methods Molecular Conformation Nanostructures - chemistry Nucleic acids Physics Self-assembly Static Electricity |
| title | Polarizability of G4-DNA Observed by Electrostatic Force Microscopy Measurements |
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