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Prevalence of American Heart Association Type VI Carotid Atherosclerotic Lesions Identified by Magnetic Resonance Imaging for Different Levels of Stenosis as Measured by Duplex Ultrasound

Prevalence of American Heart Association Type VI Carotid Atherosclerotic Lesions Identified by Magnetic Resonance Imaging for Different Levels of Stenosis as Measured by Duplex Ultrasound Tobias Saam, Hunter R. Underhill, Baocheng Chu, Norihide Takaya, Jianming Cai, Nayak L. Polissar, Chun Yuan, Tho...

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Published in:Journal of the American College of Cardiology 2008-03, Vol.51 (10), p.1014-1021
Main Authors: Saam, Tobias, MD, Underhill, Hunter R., MD, Chu, Baocheng, MD, PhD, Takaya, Norihide, MD, PhD, Cai, Jianming, MD, PhD, Polissar, Nayak L., PhD, Yuan, Chun, PhD, Hatsukami, Thomas S., MD
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Language:English
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Summary:Prevalence of American Heart Association Type VI Carotid Atherosclerotic Lesions Identified by Magnetic Resonance Imaging for Different Levels of Stenosis as Measured by Duplex Ultrasound Tobias Saam, Hunter R. Underhill, Baocheng Chu, Norihide Takaya, Jianming Cai, Nayak L. Polissar, Chun Yuan, Thomas S. Hatsukami A total of 192 subjects underwent bilateral carotid magnetic resonance imaging examination after evaluation with duplex ultrasound to determine stenosis; 175 of the patients had data that could be analyzed. The presence of complicated American Heart Association type VI lesions (AHA-LT6) (luminal surface defect, hemorrhage/thrombus, or calcified nodule) was evaluated in arteries with all levels of stenosis. Although prevalence of AHA-LT6 was more prominent in vessels with severe stenosis, it was also present in 8.1% of arteries with 1% to 15% stenosis and 21.7% of arteries with 16% to 49% stenosis. These findings indicate that complex lesions develop in a substantial number of arteries in the absence of high-grade stenosis. The predictive value of these findings will be determined in ongoing prospective studies.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2007.10.054