The Final 10-Year Follow-Up Results From the BARI Randomized Trial

• Published in: Journal of the American College of Cardiology 2007-04, Vol.49 (15), p.1600-1606
• Main Authors: The BARI Investigators, BARI Investigators
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Angina; Angioplasty; Angioplasty, Balloon, Coronary - adverse effects; Angioplasty, Balloon, Coronary - methods; Biological and medical sciences; Bypasses; Cardiology; Cardiology. Vascular system; Cardiovascular; Coronary Angiography; Coronary artery; Coronary Artery Bypass - adverse effects; Coronary Artery Bypass - methods; Coronary artery disease; Coronary Disease - diagnostic imaging; Coronary Disease - mortality; Coronary Disease - therapy; Coronary vessels; Diabetes mellitus; Evaluation Studies as Topic; Female; Follow-Up Studies; Heart attacks; Heart diseases; Heart surgery; Humans; Internal Medicine; Male; Medical sciences; Middle Aged; Mortality; Patients; Probability; Proportional Hazards Models; Risk Assessment; Severity of Illness Index; Subgroups; Survival; Survival Rate; Time Factors; Treatment Outcome; Vascular Patency - physiology; Whitlow
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2006.11.048

The Final 10-Year Follow-Up Results From the BARI (Bypass Angioplasty Revascularization Investigation) Randomized Trial Maria Mori Brooks, Edwin L. Alderman, Eric Bates, Martial Bourassa, Robert M. Califf, Bernard R. Chaitman, Katherine M. Detre, Frederick Feit, Robert L. Frye, Raymond J. Gibbons, Regina M. Hardison, Mark A. Hlatky, David R. Holmes, Jr, Alice K. Jacobs, Sheryl F. Kelsey, Mary Krauland, William J. Rogers, Hartzell V. Schaff, Leonard Schwartz, Kim Sutton-Tyrrell, David O. Williams, Patrick L. Whitlow, for the BARI Investigators In the BARI (Bypass Angioplasty Revascularization Investigation) study, 1,829 patients with multivessel coronary artery disease were randomly assigned to percutaneous transluminal coronary balloon angioplasty (PTCA) or coronary artery bypass grafting (CABG) and followed up for an average of 10.4 years. The 10-year survival was 71.0% for PTCA and 73.5% for CABG (p = 0.18). The PTCA patients had substantially more subsequent revascularization procedures than the CABG group, but similar rates of angina. In the subgroup of patients with no treated diabetes, survival rates were nearly identical by randomization, whereas in the subgroup with treated diabetes, the CABG group had higher survival than the PTCA group (PTCA 45.5% vs. CABG 57.8%, p = 0.025).