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Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production
Investigation of antiinflammatory constituents of the stem and root barks of Ulmus davidiana var. japonica resulted in the isolation of three guaiane type sesquiterpenes, torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-...
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| Published in: | Fitoterapia 2007-04, Vol.78 (3), p.196-199 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c390t-b8655f78e810b9e76465bda9129d35cc5ead503c55ddb467fa43333cdc0a6a603 |
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| cites | cdi_FETCH-LOGICAL-c390t-b8655f78e810b9e76465bda9129d35cc5ead503c55ddb467fa43333cdc0a6a603 |
| container_end_page | 199 |
| container_issue | 3 |
| container_start_page | 196 |
| container_title | Fitoterapia |
| container_volume | 78 |
| creator | Kim, Young Choong Lee, Mi Kyeong Sung, Sang Hyun Kim, Seung Hyun |
| description | Investigation of antiinflammatory constituents of the stem and root barks of
Ulmus davidiana var.
japonica resulted in the isolation of three guaiane type sesquiterpenes, torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-hydroxytorilin A. All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells. |
| doi_str_mv | 10.1016/j.fitote.2006.11.013 |
| format | article |
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All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells.</description><subject>1-Hydroxytorilin A</subject><subject>Animals</subject><subject>Anti-Inflammatory Agents - administration & dosage</subject><subject>Anti-Inflammatory Agents - pharmacology</subject><subject>Anti-Inflammatory Agents - therapeutic use</subject><subject>Antiinflammatory activity</subject><subject>Biological and medical sciences</subject><subject>Cells, Cultured</subject><subject>Dose-Response Relationship, Drug</subject><subject>General pharmacology</subject><subject>Guaianes</subject><subject>Lipopolysaccharides</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Nitric Oxide - antagonists & inhibitors</subject><subject>Nitric Oxide - biosynthesis</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Phytotherapy</subject><subject>Plant Extracts - administration & dosage</subject><subject>Plant Extracts - pharmacology</subject><subject>Plant Extracts - therapeutic use</subject><subject>Plant Roots</subject><subject>Plant Stems</subject><subject>Sesquiterpenes - administration & dosage</subject><subject>Sesquiterpenes - pharmacology</subject><subject>Sesquiterpenes - therapeutic use</subject><subject>Ulmus</subject><subject>Ulmus davidiana var. japonica</subject><issn>0367-326X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNp9kE2LFDEQhvuguOvqPxDJRW_dJpNOevoiyLJ-wIIHXfAWqpNqpobupDdJj87ZP26GGdibdSkonreqeKrqjeCN4EJ_2Dcj5ZCx2XCuGyEaLuSz6ppL3dVyo39dVS9T2nMulGzFi-pKdLKVfb-5rv7-wPS4Usa4oMfExhhm9jDNa2IODuQIPLADxIbtYQmeLLDflHcs75CR39FQ7sYjw3FEmxMLnk20hCVMxwTW7iCSw5q8Wy065ilHsiz8KUO2xFCmmYJ_VT0fYUr4-tJvqofPdz9vv9b33798u_10X1vZ81wPW63U2G1xK_jQY6dbrQYHvdj0TiprFYJTXFqlnBta3Y3QylLWWQ4aNJc31fvz3nL6ccWUzUzJ4jSBx7Am03G5bYU6ge0ZtDGkFHE0S6QZ4tEIbk7Czd6chZuTcCOEKcJL7O1l_zrM6J5CF9sFeHcBIFmYxgjeUnritrrXQonCfTxzWGwcCKNJltAXhRSLZuMC_f-TfxBapnw</recordid><startdate>20070401</startdate><enddate>20070401</enddate><creator>Kim, Young Choong</creator><creator>Lee, Mi Kyeong</creator><creator>Sung, Sang Hyun</creator><creator>Kim, Seung Hyun</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070401</creationdate><title>Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production</title><author>Kim, Young Choong ; Lee, Mi Kyeong ; Sung, Sang Hyun ; Kim, Seung Hyun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c390t-b8655f78e810b9e76465bda9129d35cc5ead503c55ddb467fa43333cdc0a6a603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>1-Hydroxytorilin A</topic><topic>Animals</topic><topic>Anti-Inflammatory Agents - administration & dosage</topic><topic>Anti-Inflammatory Agents - pharmacology</topic><topic>Anti-Inflammatory Agents - therapeutic use</topic><topic>Antiinflammatory activity</topic><topic>Biological and medical sciences</topic><topic>Cells, Cultured</topic><topic>Dose-Response Relationship, Drug</topic><topic>General pharmacology</topic><topic>Guaianes</topic><topic>Lipopolysaccharides</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Nitric Oxide - antagonists & inhibitors</topic><topic>Nitric Oxide - biosynthesis</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>Phytotherapy</topic><topic>Plant Extracts - administration & dosage</topic><topic>Plant Extracts - pharmacology</topic><topic>Plant Extracts - therapeutic use</topic><topic>Plant Roots</topic><topic>Plant Stems</topic><topic>Sesquiterpenes - administration & dosage</topic><topic>Sesquiterpenes - pharmacology</topic><topic>Sesquiterpenes - therapeutic use</topic><topic>Ulmus</topic><topic>Ulmus davidiana var. japonica</topic><toplevel>online_resources</toplevel><creatorcontrib>Kim, Young Choong</creatorcontrib><creatorcontrib>Lee, Mi Kyeong</creatorcontrib><creatorcontrib>Sung, Sang Hyun</creatorcontrib><creatorcontrib>Kim, Seung Hyun</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fitoterapia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Young Choong</au><au>Lee, Mi Kyeong</au><au>Sung, Sang Hyun</au><au>Kim, Seung Hyun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production</atitle><jtitle>Fitoterapia</jtitle><addtitle>Fitoterapia</addtitle><date>2007-04-01</date><risdate>2007</risdate><volume>78</volume><issue>3</issue><spage>196</spage><epage>199</epage><pages>196-199</pages><issn>0367-326X</issn><abstract>Investigation of antiinflammatory constituents of the stem and root barks of
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japonica resulted in the isolation of three guaiane type sesquiterpenes, torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-hydroxytorilin A. All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>17343992</pmid><doi>10.1016/j.fitote.2006.11.013</doi><tpages>4</tpages></addata></record> |
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| ispartof | Fitoterapia, 2007-04, Vol.78 (3), p.196-199 |
| issn | 0367-326X |
| language | eng |
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| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | 1-Hydroxytorilin A Animals Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Antiinflammatory activity Biological and medical sciences Cells, Cultured Dose-Response Relationship, Drug General pharmacology Guaianes Lipopolysaccharides Medical sciences Mice Nitric Oxide - antagonists & inhibitors Nitric Oxide - biosynthesis Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Roots Plant Stems Sesquiterpenes - administration & dosage Sesquiterpenes - pharmacology Sesquiterpenes - therapeutic use Ulmus Ulmus davidiana var. japonica |
| title | Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production |
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