The Helical Ventricular Myocardial Band of Torrent-Guasp

We live in an era of substantial progress in understanding myocardial structure and function at genetic, molecular, and microscopic levels. Yet, ventricular myocardium has proven remarkably resistant to macroscopic analyses of functional anatomy. Pronounced and practically indefinite global and loca...

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Published in:Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual 2007, Vol.10 (1), p.52-60
Main Authors: Kocica, Mladen J, Corno, Antonio F, Lackovic, Vesna, Kanjuh, Vladimir I
Format: Article
Language:English
Subjects:
Cardiothoracic Surgery
Cardiovascular Physiological Phenomena
Heart Ventricles - anatomy & histology
Heart Ventricles - ultrastructure
Helical ventricular myocardial band of Torrent-Guasp
Humans
Myocardium - ultrastructure
Pediatrics
Ventricular Function
ventricular myocardium
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Summary:We live in an era of substantial progress in understanding myocardial structure and function at genetic, molecular, and microscopic levels. Yet, ventricular myocardium has proven remarkably resistant to macroscopic analyses of functional anatomy. Pronounced and practically indefinite global and local structural anisotropy of its fibers and other ventricular wall constituents produces electrical and mechanical properties that are nonlinear, anisotropic, time varying, and spatially inhomogeneous. The helical ventricular myocardial band of Torrent-Guasp is a revolutionary new concept in understanding global, 3-dimensional, functional architecture of the ventricular myocardium. This concept defines the principal, cumulative vectors, integrating the tissue architecture (ie, form) and net forces developed (ie, function) within the ventricular mass. The primary purpose of this review is to emphasize the importance of this concept, in the light of collaborative efforts to establish an integrative approach, defining ventricular form and function by linking across multiple scales of biological organization, as explained in the ongoing Physiome project. Because one of the most important scientific missions in this century is integration of basic research with clinical medicine, we believe that this knowledge is not of merely academic importance, but is also the essential prerequisite in clinical evaluation and treatment of different heart diseases.
ISSN:1092-9126
DOI:10.1053/j.pcsu.2007.01.006