Viral Load in Blood Is Correlated with Disease Severity of Neonatal Coxsackievirus B3 Infection: Early Diagnosis and Predicting Disease Severity Is Possible in Severe Neonatal Enterovirus Infection

We conducted a study during an outbreak of coxsackievirus B3 infection in 2005 and found that viral RNA could be detected in patients' blood specimens soon after the onset of fever, and the level of viral RNA was positively correlated with disease severity. Timely diagnosis is possible in sever...

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Bibliographic Details
Published in:Clinical infectious diseases 2007-05, Vol.44 (10), p.e78-e81
Main Authors: Yen, Meng-Hsiu, Tsao, Kuo-Chien, Huang, Yhu-Chering, Huang, Chung-Guei, Huang, Ya-Ling, Lin, Reyin, Chang, Mei-Ling, Huang, Chi-Chia, Yan, Dah-Chin, Lin, Tzou-Yien
Format: Article
Language:English
Subjects:
Coxsackievirus B3
Coxsackievirus Infections - blood
Coxsackievirus Infections - epidemiology
Coxsackievirus Infections - virology
Disease Outbreaks
Enterovirus
Enterovirus B, Human - genetics
Enterovirus B, Human - growth & development
Humans
Infant
Infant, Newborn
Reverse Transcriptase Polymerase Chain Reaction - methods
RNA, Viral - blood
Severity of Illness Index
Taiwan - epidemiology
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Summary:We conducted a study during an outbreak of coxsackievirus B3 infection in 2005 and found that viral RNA could be detected in patients' blood specimens soon after the onset of fever, and the level of viral RNA was positively correlated with disease severity. Timely diagnosis is possible in severe neonatal enterovirus infection.
ISSN:1058-4838
1537-6591
DOI:10.1086/515399