Pulmonary mucormycosis (Cunninghamella bertholletiae) with cavitation diagnosed using ultra‐thin fibre‐optic bronchoscopy

:  Recently, ultra‐thin bronchoscopy has made it possible to observe smaller bronchi not visualized using standard techniques. We describe a case of pulmonary mucormycosis with cavitation, diagnosed using an ultra‐thin bronchoscope. A 15‐year‐old girl with acute myeloid leukaemia had taken oral pred...

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Bibliographic Details
Published in:Respirology (Carlton, Vic.) Vic.), 2008-03, Vol.13 (2), p.312-314
Main Authors: YAGI, Shin‐ichi, MIYASHITA, Naoyuki, FUKUDA, Minoru, OBASE, Yasushi, YOSHIDA, Koichiro, MIYAUCHI, Ayaka, KAWASAKI, Kouzou, SODA, Hiroshi, OKA, Mikio
Format: Article
Language:English
Subjects:
Adolescent
bronchoscope
Bronchoscopes
Bronchoscopy
Cunninghamella
Cunninghamella bertholletiae
Equipment Design
Female
Humans
immunocompromised host
Lung Diseases, Fungal - diagnosis
mucormycosis
Mucormycosis - diagnosis
opportunistic infection
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Summary::  Recently, ultra‐thin bronchoscopy has made it possible to observe smaller bronchi not visualized using standard techniques. We describe a case of pulmonary mucormycosis with cavitation, diagnosed using an ultra‐thin bronchoscope. A 15‐year‐old girl with acute myeloid leukaemia had taken oral prednisolone, 60 mg/day, for graft versus host disease after haematopoietic stem cell transplantation. She was admitted to our hospital with fever and a large cavitary lesion in the right hilum. Using an ultra‐thin bronchoscope, the interior of the cavity in the superior segment of the right lower lobe was observed. The bronchoscopic findings revealed debris adhering to the cavity wall with a small volume of effusion. Cunninghamella bertholletiae was isolated from the effusion specimen obtained using the bronchoscope. Pulmonary mucormycosis (C. bertholletiae) complicating an immunocompromised state was diagnosed. Ultra‐thin bronchoscopy is useful to diagnose complex pulmonary infections and more research is needed to verify its clinical indications and utility.
ISSN:1323-7799
1440-1843
DOI:10.1111/j.1440-1843.2008.01240.x