IgA nephropathy associated with leukemia and lymphoma: report of two cases

IgA nephropathy (IgAN) associated with leukemia and lymphoma has not, to our knowledge, been reported in children. Two children suffering from these diseases are described here. One patient developed IgAN at the end of 5 years’ chemotherapy for acute lymphocytic leukemia. The other had microscopic h...

Full description

Saved in:
Bibliographic Details
Published in:Clinical and experimental nephrology 2008-04, Vol.12 (2), p.140-143
Main Authors: Motoyama, Osamu, Kojima, Yasuko, Ohara, Akira, Tsukimoto, Ichirou, Ishikawa, Yukio, Iitaka, Kikuo
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - administration & dosage
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Case Report
Child
Child, Preschool
Dipyridamole - therapeutic use
Female
Glomerulonephritis, IGA - complications
Glomerulonephritis, IGA - drug therapy
Glomerulonephritis, IGA - immunology
Glomerulonephritis, IGA - pathology
Hematuria - etiology
Hematuria - pathology
Humans
Immunoglobulin A - blood
Immunosuppressive Agents - administration & dosage
Kidney Glomerulus - immunology
Kidney Glomerulus - ultrastructure
Lymphoma, B-Cell - complications
Lymphoma, B-Cell - drug therapy
Lymphoma, B-Cell - immunology
Lymphoma, B-Cell - pathology
Male
Medicine
Medicine & Public Health
Nephrology
Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications
Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma - immunology
Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology
Urology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:IgA nephropathy (IgAN) associated with leukemia and lymphoma has not, to our knowledge, been reported in children. Two children suffering from these diseases are described here. One patient developed IgAN at the end of 5 years’ chemotherapy for acute lymphocytic leukemia. The other had microscopic hematuria 3 years before the onset of non-Hodgkin lymphoma, and hematuria continued during chemotherapy. Each disease occurred after a long interval, and the clinical courses did not run parallel. The association was thought to be incidental in our cases. Chemotherapy with adrenocorticosteroids and immunosuppressants [6-mercaptopurine (6-MP) and cyclophosphamide (CY)] for leukemia and lymphoma did not affect the clinical course of IgAN.
ISSN:1342-1751
1437-7799
DOI:10.1007/s10157-007-0009-2