Predictors of Left Ventricular Thrombus Formation in Acute Myocardial Infarction Treated With Successful Primary Angioplasty With Stenting

There are limited data referring to the incidence of left ventricle (LV) thrombus formation after successful primary percutaneous coronary intervention (PCI) with stenting, which is now the treatment of choice in patients with acute myocardial infarction (AMI). Previously reported results were often...

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Bibliographic Details
Published in:The American journal of the medical sciences 2008-03, Vol.335 (3), p.171-176
Main Authors: Zielinska, Marzenna, Kaczmarek, Krzysztof, Tylkowski, Michał
Format: Article
Language:English
Subjects:
Aged
Angioplasty, Balloon, Coronary - methods
Biological and medical sciences
Cardiology. Vascular system
Coronary Angiography
Coronary heart disease
Coronary Thrombosis - physiopathology
Coronary Thrombosis - surgery
Echocardiography
Female
General aspects
Heart
Humans
Left ventricular thrombus
Male
Medical sciences
Middle Aged
Myocardial Infarction - surgery
Primary stenting
Prognosis
Retrospective Studies
Stents
Ventricular Dysfunction, Left - diagnostic imaging
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Summary:There are limited data referring to the incidence of left ventricle (LV) thrombus formation after successful primary percutaneous coronary intervention (PCI) with stenting, which is now the treatment of choice in patients with acute myocardial infarction (AMI). Previously reported results were often based on low or heterogeneous patient populations. To evaluate the prevalence of LV thrombus in the early period of AMI, 2,911 patients who had undergone successful primary stenting were retrospectively studied. Baseline demographic characteristics, angiographic findings, and antiplatelet treatment were analyzed to find predictors of thrombus formation. LV thrombus was diagnosed by 2-dimensional echocardiography within 3 to 5days after PCI. This complication was detected in 73 patients (2.5%). Patients with thrombus and patients without it were at the same age and had diabetes mellitus, prior myocardial infarction, and lipid disorders at the same frequency. The extent of coronary artery disease was similar in both groups. The incidence of LV thrombi was similar in patients treated with and without glycoprotein IIb/IIIa inhibitors (2.02% vs 2.9%, NS). According to results of multiple log-regression analysis, the presence of LV thrombus was strongly associated with anterior AMI, ejection fraction
ISSN:0002-9629
1538-2990
DOI:10.1097/MAJ.0b013e318142be20