The range and demographics of salivary gland tumours diagnosed in a UK population

Summary Salivary gland tumours are relatively rare and comprise a diverse range of neoplasms. The aim of this study was to determine the range and demographics of all histologically diagnosed salivary tumours in a European population. All entries for salivary gland tumours from 1974 to 2005 inclusiv...

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Bibliographic Details
Published in:Oral oncology 2008-04, Vol.44 (4), p.407-417
Main Authors: Jones, A.V, Craig, G.T, Speight, P.M, Franklin, C.D
Format: Article
Language:English
Subjects:
Adenolymphoma - epidemiology
Adenolymphoma - pathology
Adenoma - epidemiology
Adenoma - pathology
Adenoma, Pleomorphic - epidemiology
Adenoma, Pleomorphic - pathology
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Biological and medical sciences
Carcinoma, Mucoepidermoid - epidemiology
Carcinoma, Mucoepidermoid - pathology
Child
Demographics
England - epidemiology
Epidemiology
Female
Hematology, Oncology and Palliative Medicine
Humans
Male
Medical sciences
Middle Aged
Otolaryngology
Otorhinolaryngology. Stomatology
Salivary Gland Neoplasms - epidemiology
Salivary Gland Neoplasms - pathology
Salivary glands
Salivary Glands, Minor
Sex Distribution
Tumors
Tumours
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Summary:Summary Salivary gland tumours are relatively rare and comprise a diverse range of neoplasms. The aim of this study was to determine the range and demographics of all histologically diagnosed salivary tumours in a European population. All entries for salivary gland tumours from 1974 to 2005 inclusive were retrieved and analysed for each diagnosis including number of specimens, male:female ratio and age range. These data were then analysed for the distribution of benign and malignant salivary tumours in major and minor salivary glands. 58,880 specimens were received; of these, 741 cases (1.3% of all specimens) were diagnosed as salivary gland tumours with a male to female ratio of 0.7:1. There were 481 (64.9%) benign and 260 (35.1%) malignant neoplasms, with the most common tumours being pleomorphic adenoma and mucoepidermoid carcinoma, respectively. Our study provides demographic data on a large series of salivary gland tumours in a European population. Accurate diagnosis is essential as salivary lesions have diverse clinical and prognostic outcomes. This study has confirmed that some tumours have a predilection for certain sites and that the risk of malignant disease is also greater at specific sites within the oral cavity.
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2007.05.010