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Microbiaeratin, a New Natural Indole Alkaloid from a Microbispora aerata Strain, Isolated from Livingston Island, Antarctica

A new sulphur-containing natural alkaloid named microbiaeratin (1a) was isolated, together with the known microbiaeratinin (2, bacillamide) from the culture filtrate of Microbispora aerata strain IMBAS-11A. The organism was isolated from penguin excrements collected on the Antarctic Livingston Islan...

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Published in:Preparative biochemistry & biotechnology 2007-04, Vol.37 (2), p.161-168
Main Authors: Ivanova, Veneta, Kolarova, Mariana, Aleksieva, Krasja, Gräfe, Udo, Dahse, Hans-Martin, Laatsch, Hartmut
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container_issue 2
container_start_page 161
container_title Preparative biochemistry & biotechnology
container_volume 37
creator Ivanova, Veneta
Kolarova, Mariana
Aleksieva, Krasja
Gräfe, Udo
Dahse, Hans-Martin
Laatsch, Hartmut
description A new sulphur-containing natural alkaloid named microbiaeratin (1a) was isolated, together with the known microbiaeratinin (2, bacillamide) from the culture filtrate of Microbispora aerata strain IMBAS-11A. The organism was isolated from penguin excrements collected on the Antarctic Livingston Island. The structure was elucidated by one- and two-dimensional NMR experiments and mass spectrometric investigations.
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subjects Actinomycetales - chemistry
Actinomycetales - genetics
Actinomycetales - physiology
Animals
Antarctic Regions
Bacillamide
Bacteria - drug effects
Bacteria - growth & development
Cell Line, Tumor - drug effects
Chromatography, High Pressure Liquid
Feces - chemistry
Feces - microbiology
Fibroblasts - cytology
Fibroblasts - drug effects
Humans
Indole Alkaloids - chemistry
Indole Alkaloids - isolation & purification
Indole Alkaloids - pharmacology
Mice
Microbiaeratin
Microbiaeratinin
Microbispora aerata
Molecular Structure
Spectrum Analysis
Spheniscidae
Sulfur - chemistry
Sulphur-containing indole alkaloids
title Microbiaeratin, a New Natural Indole Alkaloid from a Microbispora aerata Strain, Isolated from Livingston Island, Antarctica
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