Emissive Terbium Probe for Multiphoton in Vitro Cell Imaging

A polymeric terbium complex that can be excited by near-infrared excitation at 800 nm via multiphoton absorption processes has been synthesized. This complex has been demonstrated to show strong, observable, three-photon-induced f−f emission in cell imaging. In vitro studies carried out in three car...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American Chemical Society 2008-03, Vol.130 (12), p.3714-3715
Main Authors: Law, Ga-Lai, Wong, Ka-Leung, Man, Cornelia Wing-Yin, Wong, Wing-Tak, Tsao, Sai-Wah, Lam, Michael Hon-Wah, Lam, Paul Kwan-Sing
Format: Article
Language:English
Subjects:
Carcinoma - metabolism
Cell Line, Tumor
Cell Membrane - chemistry
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
HeLa Cells
Humans
Image Enhancement - instrumentation
Image Enhancement - methods
Ligands
Microscopy, Confocal - instrumentation
Microscopy, Confocal - methods
Models, Molecular
Organometallic Compounds - chemical synthesis
Organometallic Compounds - chemistry
Photons
Polymers - chemistry
Spectrometry, Fluorescence - instrumentation
Spectrometry, Fluorescence - methods
Terbium - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A polymeric terbium complex that can be excited by near-infrared excitation at 800 nm via multiphoton absorption processes has been synthesized. This complex has been demonstrated to show strong, observable, three-photon-induced f−f emission in cell imaging. In vitro studies carried out in three carcinoma cell lines (A549, HONE1, and HeLa) have been performed and shown to have low cytotoxicity. This complex is therefore a potential candidate for future infrared excitation imaging dyes.
ISSN:0002-7863
1520-5126
DOI:10.1021/ja710418d