Changes in fat-free mass during significant weight loss: a systematic review

Objective: To identify the proportion of weight lost as fat-free mass (FFM) by various weight loss interventions. Methods: Medline and Embase were systematically searched for reliable measurements of FFM before and after weight loss of >10 kg and eligible data were pooled. In a fixed effect model...

Full description

Saved in:
Bibliographic Details
Published in:International Journal of Obesity 2007-05, Vol.31 (5), p.743-750
Main Authors: Chaston, T.B, Dixon, J.B, O'Brien, P.E
Format: Article
Language:English
Subjects:
Absorptiometry, Photon
bariatric surgery
behavior modification
Biological and medical sciences
Body composition
Body Composition - physiology
cohort studies
Diet, Reducing
Dietary restrictions
Epidemiology
Exercise
fat free mass
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Health aspects
Health Promotion and Disease Prevention
human nutrition
Humans
Internal Medicine
Linear Models
literature reviews
low calorie diet
Male
Medical sciences
Medicine
Medicine & Public Health
Metabolic Diseases
Methods
nutritional intervention
Obesity
Obesity - diet therapy
Obesity - surgery
Obesity - therapy
Physiological aspects
Public Health
Randomized Controlled Trials as Topic
Regression analysis
review
Surgery
Systematic review
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Weight loss
Weight Loss - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective: To identify the proportion of weight lost as fat-free mass (FFM) by various weight loss interventions. Methods: Medline and Embase were systematically searched for reliable measurements of FFM before and after weight loss of >10 kg and eligible data were pooled. In a fixed effect model of % FFM loss/weight loss (%FFML), linear regression analysis was used to determine the influence of degree of caloric restriction, exercise, magnitude of weight loss, initial body mass index (BMI) and type of surgery. Results: Data were included from 26 cohorts treated with dietary and behavioral interventions and 29 cohorts of bariatric surgery patients. The degree of caloric restriction was positively associated with %FFML (r 2=0.31, P=0.006) and in three randomized controlled trials exercise was shown to decrease %FFML. Compared with laparoscopic adjustable gastric banding (LAGB), biliopancreatic diversion (BPD) and roux en Y gastric bypass (RYGB) caused greater log(e) (natural log) %FFML (r 2=0.453, P
ISSN:0307-0565
1476-5497
DOI:10.1038/sj.ijo.0803483