Loading…

Biomechanical, microvascular, and cellular factors promote muscle and bone regeneration

It is becoming clear that the long-term outcome of complex bone injuries benefits from approaches that selectively target biomechanical, vascular, and cellular pathways. The typically held view of either biological or mechanical aspects of healing is oversimplified and does not correspond to clinica...

Full description

Saved in:

Bibliographic Details
Published in:	Exercise and sport sciences reviews 2008-04, Vol.36 (2), p.64-70
Main Authors:	Duda, Georg N, Taylor, William R, Winkler, Tobias, Matziolis, Georg, Heller, Markus O, Haas, Norbert P, Perka, Carsten, Schaser, Klaus-D
Format:	Article
Language:	English
Subjects:	Animals Biomechanical Phenomena Bone Regeneration - physiology Collateral Circulation - physiology Exercise - physiology Femur - physiopathology Fractures, Bone - metabolism Humans Microcirculation - physiology Muscle, Skeletal - blood supply Muscle, Skeletal - physiology Periosteum - physiology Walking - physiology Wound Healing - physiology
Citations:	Items that this one cites Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

cited_by	cdi_FETCH-LOGICAL-c382t-953ced54574dd597576bba559022dc3eb884e3eeda8f04a9685945bf8afbd9723
cites	cdi_FETCH-LOGICAL-c382t-953ced54574dd597576bba559022dc3eb884e3eeda8f04a9685945bf8afbd9723
container_end_page	70
container_issue	2
container_start_page	64
container_title	Exercise and sport sciences reviews
container_volume	36
creator	Duda, Georg N Taylor, William R Winkler, Tobias Matziolis, Georg Heller, Markus O Haas, Norbert P Perka, Carsten Schaser, Klaus-D
description	It is becoming clear that the long-term outcome of complex bone injuries benefits from approaches that selectively target biomechanical, vascular, and cellular pathways. The typically held view of either biological or mechanical aspects of healing is oversimplified and does not correspond to clinical reality. The fundamental mechanisms of soft tissue regeneration most likely hold the key to understanding healing response.
doi_str_mv	10.1097/JES.0b013e318168eb88
format	article
fullrecord	<record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70429253</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>19423647</sourcerecordid><originalsourceid>FETCH-LOGICAL-c382t-953ced54574dd597576bba559022dc3eb884e3eeda8f04a9685945bf8afbd9723</originalsourceid><addsrcrecordid>eNqFkMtKw0AUhmeh2Fp9A5GsXLV1rpmZpUq9UXCh4jLM5UQjSabOJIJvb2ILghtXhwPf_3POh9AJwUuCtTy_Xz0uscWEASOK5AqsUntoirEmi5wxMkGHKb1jTDFl5ABNiGI5zZWcopfLKjTg3kxbOVPPs6ZyMXya5PraxHlmWp85qOtxy0rjuhBTtomhCR1kTZ9cDT-MDS1kEV6hhWi6KrRHaL80dYLj3Zyh5-vV09XtYv1wc3d1sV44pmi30II58IILyb0XWgqZW2uE0JhS79j4BwcG4I0qMTc6V0JzYUtlSuu1pGyGzra9w1EfPaSuaKo0XmxaCH0qJOZUU8H-BYnmlOVcDiDfgoOIlCKUxSZWjYlfBcHFaLsYbBd_bQ-x011_bxvwv6GdavYN7Sx_OA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19423647</pqid></control><display><type>article</type><title>Biomechanical, microvascular, and cellular factors promote muscle and bone regeneration</title><source>HEAL-Link subscriptions: Lippincott Williams & Wilkins</source><creator>Duda, Georg N ; Taylor, William R ; Winkler, Tobias ; Matziolis, Georg ; Heller, Markus O ; Haas, Norbert P ; Perka, Carsten ; Schaser, Klaus-D</creator><creatorcontrib>Duda, Georg N ; Taylor, William R ; Winkler, Tobias ; Matziolis, Georg ; Heller, Markus O ; Haas, Norbert P ; Perka, Carsten ; Schaser, Klaus-D</creatorcontrib><description>It is becoming clear that the long-term outcome of complex bone injuries benefits from approaches that selectively target biomechanical, vascular, and cellular pathways. The typically held view of either biological or mechanical aspects of healing is oversimplified and does not correspond to clinical reality. The fundamental mechanisms of soft tissue regeneration most likely hold the key to understanding healing response.</description><identifier>ISSN: 0091-6331</identifier><identifier>DOI: 10.1097/JES.0b013e318168eb88</identifier><identifier>PMID: 18362687</identifier><language>eng</language><publisher>United States</publisher><subject>Animals ; Biomechanical Phenomena ; Bone Regeneration - physiology ; Collateral Circulation - physiology ; Exercise - physiology ; Femur - physiopathology ; Fractures, Bone - metabolism ; Humans ; Microcirculation - physiology ; Muscle, Skeletal - blood supply ; Muscle, Skeletal - physiology ; Periosteum - physiology ; Walking - physiology ; Wound Healing - physiology</subject><ispartof>Exercise and sport sciences reviews, 2008-04, Vol.36 (2), p.64-70</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c382t-953ced54574dd597576bba559022dc3eb884e3eeda8f04a9685945bf8afbd9723</citedby><cites>FETCH-LOGICAL-c382t-953ced54574dd597576bba559022dc3eb884e3eeda8f04a9685945bf8afbd9723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18362687$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Duda, Georg N</creatorcontrib><creatorcontrib>Taylor, William R</creatorcontrib><creatorcontrib>Winkler, Tobias</creatorcontrib><creatorcontrib>Matziolis, Georg</creatorcontrib><creatorcontrib>Heller, Markus O</creatorcontrib><creatorcontrib>Haas, Norbert P</creatorcontrib><creatorcontrib>Perka, Carsten</creatorcontrib><creatorcontrib>Schaser, Klaus-D</creatorcontrib><title>Biomechanical, microvascular, and cellular factors promote muscle and bone regeneration</title><title>Exercise and sport sciences reviews</title><addtitle>Exerc Sport Sci Rev</addtitle><description>It is becoming clear that the long-term outcome of complex bone injuries benefits from approaches that selectively target biomechanical, vascular, and cellular pathways. The typically held view of either biological or mechanical aspects of healing is oversimplified and does not correspond to clinical reality. The fundamental mechanisms of soft tissue regeneration most likely hold the key to understanding healing response.</description><subject>Animals</subject><subject>Biomechanical Phenomena</subject><subject>Bone Regeneration - physiology</subject><subject>Collateral Circulation - physiology</subject><subject>Exercise - physiology</subject><subject>Femur - physiopathology</subject><subject>Fractures, Bone - metabolism</subject><subject>Humans</subject><subject>Microcirculation - physiology</subject><subject>Muscle, Skeletal - blood supply</subject><subject>Muscle, Skeletal - physiology</subject><subject>Periosteum - physiology</subject><subject>Walking - physiology</subject><subject>Wound Healing - physiology</subject><issn>0091-6331</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNqFkMtKw0AUhmeh2Fp9A5GsXLV1rpmZpUq9UXCh4jLM5UQjSabOJIJvb2ILghtXhwPf_3POh9AJwUuCtTy_Xz0uscWEASOK5AqsUntoirEmi5wxMkGHKb1jTDFl5ABNiGI5zZWcopfLKjTg3kxbOVPPs6ZyMXya5PraxHlmWp85qOtxy0rjuhBTtomhCR1kTZ9cDT-MDS1kEV6hhWi6KrRHaL80dYLj3Zyh5-vV09XtYv1wc3d1sV44pmi30II58IILyb0XWgqZW2uE0JhS79j4BwcG4I0qMTc6V0JzYUtlSuu1pGyGzra9w1EfPaSuaKo0XmxaCH0qJOZUU8H-BYnmlOVcDiDfgoOIlCKUxSZWjYlfBcHFaLsYbBd_bQ-x011_bxvwv6GdavYN7Sx_OA</recordid><startdate>200804</startdate><enddate>200804</enddate><creator>Duda, Georg N</creator><creator>Taylor, William R</creator><creator>Winkler, Tobias</creator><creator>Matziolis, Georg</creator><creator>Heller, Markus O</creator><creator>Haas, Norbert P</creator><creator>Perka, Carsten</creator><creator>Schaser, Klaus-D</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>7X8</scope></search><sort><creationdate>200804</creationdate><title>Biomechanical, microvascular, and cellular factors promote muscle and bone regeneration</title><author>Duda, Georg N ; Taylor, William R ; Winkler, Tobias ; Matziolis, Georg ; Heller, Markus O ; Haas, Norbert P ; Perka, Carsten ; Schaser, Klaus-D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c382t-953ced54574dd597576bba559022dc3eb884e3eeda8f04a9685945bf8afbd9723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Animals</topic><topic>Biomechanical Phenomena</topic><topic>Bone Regeneration - physiology</topic><topic>Collateral Circulation - physiology</topic><topic>Exercise - physiology</topic><topic>Femur - physiopathology</topic><topic>Fractures, Bone - metabolism</topic><topic>Humans</topic><topic>Microcirculation - physiology</topic><topic>Muscle, Skeletal - blood supply</topic><topic>Muscle, Skeletal - physiology</topic><topic>Periosteum - physiology</topic><topic>Walking - physiology</topic><topic>Wound Healing - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Duda, Georg N</creatorcontrib><creatorcontrib>Taylor, William R</creatorcontrib><creatorcontrib>Winkler, Tobias</creatorcontrib><creatorcontrib>Matziolis, Georg</creatorcontrib><creatorcontrib>Heller, Markus O</creatorcontrib><creatorcontrib>Haas, Norbert P</creatorcontrib><creatorcontrib>Perka, Carsten</creatorcontrib><creatorcontrib>Schaser, Klaus-D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><jtitle>Exercise and sport sciences reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Duda, Georg N</au><au>Taylor, William R</au><au>Winkler, Tobias</au><au>Matziolis, Georg</au><au>Heller, Markus O</au><au>Haas, Norbert P</au><au>Perka, Carsten</au><au>Schaser, Klaus-D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biomechanical, microvascular, and cellular factors promote muscle and bone regeneration</atitle><jtitle>Exercise and sport sciences reviews</jtitle><addtitle>Exerc Sport Sci Rev</addtitle><date>2008-04</date><risdate>2008</risdate><volume>36</volume><issue>2</issue><spage>64</spage><epage>70</epage><pages>64-70</pages><issn>0091-6331</issn><abstract>It is becoming clear that the long-term outcome of complex bone injuries benefits from approaches that selectively target biomechanical, vascular, and cellular pathways. The typically held view of either biological or mechanical aspects of healing is oversimplified and does not correspond to clinical reality. The fundamental mechanisms of soft tissue regeneration most likely hold the key to understanding healing response.</abstract><cop>United States</cop><pmid>18362687</pmid><doi>10.1097/JES.0b013e318168eb88</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
fulltext	fulltext
identifier	ISSN: 0091-6331
ispartof	Exercise and sport sciences reviews, 2008-04, Vol.36 (2), p.64-70
issn	0091-6331
language	eng
recordid	cdi_proquest_miscellaneous_70429253
source	HEAL-Link subscriptions: Lippincott Williams & Wilkins
subjects	Animals Biomechanical Phenomena Bone Regeneration - physiology Collateral Circulation - physiology Exercise - physiology Femur - physiopathology Fractures, Bone - metabolism Humans Microcirculation - physiology Muscle, Skeletal - blood supply Muscle, Skeletal - physiology Periosteum - physiology Walking - physiology Wound Healing - physiology
title	Biomechanical, microvascular, and cellular factors promote muscle and bone regeneration
url	http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T19%3A58%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Biomechanical,%20microvascular,%20and%20cellular%20factors%20promote%20muscle%20and%20bone%20regeneration&rft.jtitle=Exercise%20and%20sport%20sciences%20reviews&rft.au=Duda,%20Georg%20N&rft.date=2008-04&rft.volume=36&rft.issue=2&rft.spage=64&rft.epage=70&rft.pages=64-70&rft.issn=0091-6331&rft_id=info:doi/10.1097/JES.0b013e318168eb88&rft_dat=%3Cproquest_cross%3E19423647%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c382t-953ced54574dd597576bba559022dc3eb884e3eeda8f04a9685945bf8afbd9723%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=19423647&rft_id=info:pmid/18362687&rfr_iscdi=true