A multicenter study of the pharmacokinetics of lisinopril in pediatric patients with hypertension

The pharmacokinetic (PK) parameters of lisinopril were obtained in 46 children aged 6 months to 15 years. A lisinopril suspension (0.15 mg/kg per day) was administered to patients

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2007-05, Vol.22 (5), p.695-701
Main Authors: Hogg, Ronald J, Delucchi, Angela, Sakihara, Graciela, Wells, Thomas G, Tenney, Frank, Batisky, Donald L, Blumer, Jeffrey L, Vogt, Beth A, Lo, Man-Wai, Hand, Elizabeth, Panebianco, Deborah, Rippley, Ronda, Shaw, Wayne, Shahinfar, Shahnaz
Format: Article
Language:English
Subjects:
Adolescent
Age groups
Antihypertensive Agents - blood
Antihypertensive Agents - pharmacokinetics
Antihypertensive Agents - therapeutic use
Antihypertensives
Blood Specimen Collection
Care and treatment
Child
Child, Preschool
Dosage and administration
Drug dosages
Female
Glomerular Filtration Rate
Health aspects
Humans
Hypertension
Hypertension - drug therapy
Infant
Laboratories
Lisinopril
Lisinopril - blood
Lisinopril - pharmacokinetics
Lisinopril - therapeutic use
Male
Metabolic Clearance Rate
Pediatrics
Pharmacokinetics
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Description
Summary:The pharmacokinetic (PK) parameters of lisinopril were obtained in 46 children aged 6 months to 15 years. A lisinopril suspension (0.15 mg/kg per day) was administered to patients
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-006-0399-5