Disseminated classic Kaposi's sarcoma

• Published in: Clinical & translational oncology 2007-04, Vol.9 (4), p.255-257
• Main Authors: Fernández Pérez, I, Vázquez Tuñas, L, Lázaro Quintela, M, Lamas Domínguez, P, Gentil González, M, Carrasco Alvarez, J, López Jato, C, Castellanos Díez, J
• Format: Article
• Language: English
• Subjects: Aged; Antibiotics, Antineoplastic; Biopsy; Doxorubicin - administration & dosage; Doxorubicin - therapeutic use; Female; Follow-Up Studies; Herpesvirus 8, Human; Humans; Leg - pathology; Liver Neoplasms - diagnostic imaging; Liver Neoplasms - drug therapy; Liver Neoplasms - secondary; Lung Neoplasms - diagnostic imaging; Lung Neoplasms - drug therapy; Lung Neoplasms - secondary; Radiography, Abdominal; Radiography, Thoracic; Remission Induction; Sarcoma, Kaposi - diagnostic imaging; Sarcoma, Kaposi - drug therapy; Sarcoma, Kaposi - pathology; Skin - pathology; Skin Neoplasms - drug therapy; Skin Neoplasms - pathology; Splenic Neoplasms - diagnostic imaging; Splenic Neoplasms - drug therapy; Splenic Neoplasms - secondary; Time Factors; Tomography, X-Ray Computed
• ISSN: 1699-048X; 1699-3055
• DOI: 10.1007/s12094-007-0048-x

Kaposi's sarcoma (KS) is characterised by proliferation of vascular endothelial and lymphoreticular cells, frequently with a multicentric expression developed from a single node and evolving to multiple cutaneous lumps or plaque-like appearance. Four types of KS with similar histological patterns have been described in terms of their clinical and epidemiological features: classic KS, endemic (African) KS, iatrogenic KS and epidemic (AIDS-related) KS. The differences in clinical features are quite relevant: classic KS is usually limited to the lower extremities; whereas immunodeficiency-related diseases frequently involve several organs. A case of a 67-year-old woman with metastatic KS and unproven immunodeficiency is presented.