Recent Australian experience with hemopoietic stem and progenitor cell expansion

This review provides insight into two clinical trials conducted with ex vivo manipulated CD34+ cells. The first was an atempt to deliver a gene therapy for treatment of HIV and the second an attempt to improve rates of hemopoietic recovery with ex vivo generated myeloid cells.

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Bibliographic Details
Published in:Cytotherapy (Oxford, England) England), 2007, Vol.9 (3), p.231-235
Main Authors: Nilsson, S.K, Prince, H.M, Wall, D, Haylock, D.N
Format: Article
Language:English
Subjects:
Advanced Basic Science
Australia
Cell Proliferation
ex vivo expanded CD34+ cells
gene therapy
Hematopoietic Stem Cell Transplantation - trends
HIV Infections - therapy
Humans
Other
stem cell expansion
Stem Cells - cytology
transplantation
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Description
Summary:This review provides insight into two clinical trials conducted with ex vivo manipulated CD34+ cells. The first was an atempt to deliver a gene therapy for treatment of HIV and the second an attempt to improve rates of hemopoietic recovery with ex vivo generated myeloid cells.
ISSN:1465-3249
1477-2566
DOI:10.1080/14653240701315296