Simple clinical tests may predict severe oropharyngeal dysphagia in Parkinson's disease

Objective: To determine if simple screening tests can predict severe oropharyngeal dysphagia in subjects with Parkinson's disease. Methodology: Forty‐five subjects (26 females) of average age 75 (range: 65–94) who were classified as Modified Hoehn and Yahr stages 2 to 5 were enrolled. The prese...

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Bibliographic Details
Published in:Movement disorders 2007-04, Vol.22 (5), p.640-644
Main Authors: Lam, Kuen, Kwai Yi Lam, Florence, Kwong Lau, Kwok, Kay Chan, Yiu, Yee Ling Kan, Elaine, Woo, Jean, Kee Wong, Fat, Ko, Andrew
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
Body Mass Index
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Deglutition Disorders - diagnosis
dysphagia
Female
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Hong Kong
Humans
Male
Mass Screening
Medical sciences
Nervous system (semeiology, syndromes)
Neurologic Examination
Neurology
Parkinson Disease - diagnosis
Parkinson's disease
Prospective Studies
Risk Factors
screening
simple tests
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Summary:Objective: To determine if simple screening tests can predict severe oropharyngeal dysphagia in subjects with Parkinson's disease. Methodology: Forty‐five subjects (26 females) of average age 75 (range: 65–94) who were classified as Modified Hoehn and Yahr stages 2 to 5 were enrolled. The presence of oropharyngeal dysphagia was assessed by a symptom questionnaire, 50 ml water swallowing test and videofluroscopic swallowing study. Results: Six of the subjects had severe oropharyngeal dysphagia in videofluroscopic swallowing study. Subsequent multivariate analysis showed that 3 factors could independently predict severe oropharyngeal dysphagia. These included higher Modified Hoehn and Yahr stage (P = 0.042), low Body mass index (P = 0.014), and increased difficulty in keeping food or drink in the mouth (P = 0.047). The regression model had a positive predictive power of 96% (sensitivity: 83.3%, specificity: 97.4%). Conclusion: A combination of 3 simple clinical parameters may be useful for screening for severe oropharyngeal dysphagia as shown radiologically in subjects with Parkinson's disease. © 2007 Movement Disorder Society
ISSN:0885-3185
1531-8257
DOI:10.1002/mds.21362