Prospective direct comparison study of fractional resurfacing using different fluences and densities for skin rejuvenation in Asians

Background and Objective Fractional resurfacing is a new concept of cutaneous remodeling whereby laser‐induced zones of microthermal injury are surrounded by normal untreated tissue. The aim of this study is to compare the efficacy and complications of Fraxel laser treatment when using different flu...

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Bibliographic Details
Published in:Lasers in surgery and medicine 2007-04, Vol.39 (4), p.311-314
Main Authors: Kono, Taro, Chan, Henry H., Groff, William Frederick, Manstein, Dieter, Sakurai, Hiroyuki, Takeuchi, Masaki, Yamaki, Takashi, Soejima, Kazutaka, Nozaki, Motohiro
Format: Article
Language:English
Subjects:
Asian Continental Ancestry Group
Asians
Erythema - etiology
Female
fractional photothermolysis
Humans
hyperpigmentation
Hyperpigmentation - etiology
laser surgery
Laser Therapy
Middle Aged
Pain Measurement
Patient Satisfaction
Prospective Studies
Skin Aging - radiation effects
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Summary:Background and Objective Fractional resurfacing is a new concept of cutaneous remodeling whereby laser‐induced zones of microthermal injury are surrounded by normal untreated tissue. The aim of this study is to compare the efficacy and complications of Fraxel laser treatment when using different fluences and density settings. Study Design/Materials and Methods Thirty female Asian patients were enrolled in the study. Group 1 (n = 10); half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 8 mJ. The other half of the face was treated with eight passes at 250 MTZ/cm2 at an energy setting of 8 mJ. Group 2 (n = 10); half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 8 mJ. The other half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 16 mJ. Group 3 (n = 10); half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 16 mJ. The other half of the face was treated with eight passes at 250 MTZ/cm2 at an energy setting of 8 mJ. Ice pack cooling was used during and after laser treatment. The patients were evaluated for clinical efficacy and treatment‐related side effects. Results Pain, erythema, and swelling were observed to be significantly more evident or persisted longer in patients treated with higher densities and fluences (P
ISSN:0196-8092
1096-9101
DOI:10.1002/lsm.20484