Prevalence and risk factors for diabetic neuropathy in an urban south Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55)

Aims  This study was conducted to determine the prevalence of, and risk factors for, diabetic neuropathy (DN) in south Indian Type 2 diabetic subjects. Methods  Subjects were recruited from the Chennai Urban Rural Epidemiology Study, conducted on a representative cohort from Chennai city. A total of...

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Bibliographic Details
Published in:Diabetic medicine 2008-04, Vol.25 (4), p.407-412
Main Authors: Pradeepa, R., Rema, M., Vignesh, J., Deepa, M., Deepa, R., Mohan, V.
Format: Article
Language:English
Subjects:
Asian Indians
Biological and medical sciences
Body Composition
Cohort Studies
diabetes
Diabetes Mellitus, Type 2 - epidemiology
Diabetes. Impaired glucose tolerance
Diabetic Nephropathies - epidemiology
Diabetic Retinopathy - epidemiology
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Glucose Tolerance Test - methods
Humans
India - epidemiology
Male
Medical sciences
Middle Aged
neuropathy
Prevalence
Risk Factors
Rural Health - statistics & numerical data
Urban Health - statistics & numerical data
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vertebrates: endocrinology
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Summary:Aims  This study was conducted to determine the prevalence of, and risk factors for, diabetic neuropathy (DN) in south Indian Type 2 diabetic subjects. Methods  Subjects were recruited from the Chennai Urban Rural Epidemiology Study, conducted on a representative cohort from Chennai city. A total of 1629 diabetic subjects were included, of whom 1291 were known to have diabetes (KD) subjects and 338 were randomly selected newly detected diabetic (NDD) subjects. Neuropathy was diagnosed if vibratory perception threshold at the great toe, measured by biothesiometry, exceeded mean + 2 sd of a healthy non‐diabetic study population aged 20–45 years (cut point ≥ 20 V). Results  The overall prevalence of DN was 26.1% (age‐adjusted 13.1%) with no significant difference in gender. The prevalence of neuropathy was significantly higher in KD subjects compared with NDD subjects (27.8 vs. 19.5%, P = 0.002). The prevalence of diabetic retinopathy (24.1 vs. 15.3%, P 
ISSN:0742-3071
1464-5491
DOI:10.1111/j.1464-5491.2008.02397.x