Loading…
Prevalence and risk factors for diabetic neuropathy in an urban south Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55)
Aims This study was conducted to determine the prevalence of, and risk factors for, diabetic neuropathy (DN) in south Indian Type 2 diabetic subjects. Methods Subjects were recruited from the Chennai Urban Rural Epidemiology Study, conducted on a representative cohort from Chennai city. A total of...
Saved in:
| Published in: | Diabetic medicine 2008-04, Vol.25 (4), p.407-412 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c4667-4654c7c9696029d4b71f884a01ef6b42e74375c3b11df33b87c04d8f1c0c77b53 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c4667-4654c7c9696029d4b71f884a01ef6b42e74375c3b11df33b87c04d8f1c0c77b53 |
| container_end_page | 412 |
| container_issue | 4 |
| container_start_page | 407 |
| container_title | Diabetic medicine |
| container_volume | 25 |
| creator | Pradeepa, R. Rema, M. Vignesh, J. Deepa, M. Deepa, R. Mohan, V. |
| description | Aims This study was conducted to determine the prevalence of, and risk factors for, diabetic neuropathy (DN) in south Indian Type 2 diabetic subjects.
Methods Subjects were recruited from the Chennai Urban Rural Epidemiology Study, conducted on a representative cohort from Chennai city. A total of 1629 diabetic subjects were included, of whom 1291 were known to have diabetes (KD) subjects and 338 were randomly selected newly detected diabetic (NDD) subjects. Neuropathy was diagnosed if vibratory perception threshold at the great toe, measured by biothesiometry, exceeded mean + 2 sd of a healthy non‐diabetic study population aged 20–45 years (cut point ≥ 20 V).
Results The overall prevalence of DN was 26.1% (age‐adjusted 13.1%) with no significant difference in gender. The prevalence of neuropathy was significantly higher in KD subjects compared with NDD subjects (27.8 vs. 19.5%, P = 0.002). The prevalence of diabetic retinopathy (24.1 vs. 15.3%, P |
| doi_str_mv | 10.1111/j.1464-5491.2008.02397.x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70469687</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>70469687</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4667-4654c7c9696029d4b71f884a01ef6b42e74375c3b11df33b87c04d8f1c0c77b53</originalsourceid><addsrcrecordid>eNqNkdFu0zAUhi0EYmXwCsg3IHaRYDuOnSBxAaWMiQ1Qt4pLy3Ec6i61MzuB5iV4Zpy1KpfgC9uSv__46HwAQIxSHNfrTYopo0lOS5wShIoUkazk6e4BmB0fHoIZ4pQkGeL4BDwJYYMQJmVWPgYnuCAlJYTOwO9vXv-UrbZKQ2lr6E24hY1UvfMBNs7D2shK90ZBqwfvOtmvR2hsZOHgq7gHN_RreGEjZ2HnuqGVvXH2DezXGs7X2lpp4OoeXQ5etnDRmVpvjWvdjxFe90M9wlfz1XJxneT52VPwqJFt0M8O5ylYfVzczD8ll1_PL-bvLhNFGeMJZTlVXJWsZIiUNa04boqCSoR1wypKNKcZz1VWYVw3WVYVXCFaFw1WSHFe5dkpeLmv23l3N-jQi60JSrettNoNQXBEY-2C_xMkiJWEYRTBYg8q70LwuhGdN1vpR4GRmKSJjZjciMmNmKSJe2liF6PPD38M1VbXf4MHSxF4cQBkULJtvLTKhCNH4gxiGyxyb_fcL9Pq8b8bEB-uFtMt5pN93oRe74556W8F43Gg4vuXc_H-6vPyZp4hscz-AInrwWw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>20692610</pqid></control><display><type>article</type><title>Prevalence and risk factors for diabetic neuropathy in an urban south Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55)</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>Pradeepa, R. ; Rema, M. ; Vignesh, J. ; Deepa, M. ; Deepa, R. ; Mohan, V.</creator><creatorcontrib>Pradeepa, R. ; Rema, M. ; Vignesh, J. ; Deepa, M. ; Deepa, R. ; Mohan, V.</creatorcontrib><description>Aims This study was conducted to determine the prevalence of, and risk factors for, diabetic neuropathy (DN) in south Indian Type 2 diabetic subjects.
Methods Subjects were recruited from the Chennai Urban Rural Epidemiology Study, conducted on a representative cohort from Chennai city. A total of 1629 diabetic subjects were included, of whom 1291 were known to have diabetes (KD) subjects and 338 were randomly selected newly detected diabetic (NDD) subjects. Neuropathy was diagnosed if vibratory perception threshold at the great toe, measured by biothesiometry, exceeded mean + 2 sd of a healthy non‐diabetic study population aged 20–45 years (cut point ≥ 20 V).
Results The overall prevalence of DN was 26.1% (age‐adjusted 13.1%) with no significant difference in gender. The prevalence of neuropathy was significantly higher in KD subjects compared with NDD subjects (27.8 vs. 19.5%, P = 0.002). The prevalence of diabetic retinopathy (24.1 vs. 15.3%, P < 0.0001) and hypertension (51.1 vs. 40.0%, P < 0.0001) were higher in those with neuropathy compared with those without. The odds ratio for neuropathy in subjects with duration of diabetes > 15 years compared with ≤ 5 years was 5.7 (95% confidence interval: 3.52–9.08, P < 0.0001). Regression analysis showed age (P < 0.0001), glycated haemoglobin (P = 0.001) and duration of diabetes (P = 0.045) to be significantly associated with neuropathy.
Conclusions This cross‐sectional population‐based study shows that, among urban south Indian Type 2 diabetic subjects, the prevalence of DN is 26.1% and that DN is significantly associated with age, glycated haemoglobin and duration of diabetes.</description><identifier>ISSN: 0742-3071</identifier><identifier>EISSN: 1464-5491</identifier><identifier>DOI: 10.1111/j.1464-5491.2008.02397.x</identifier><identifier>PMID: 18294224</identifier><identifier>CODEN: DIMEEV</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Asian Indians ; Biological and medical sciences ; Body Composition ; Cohort Studies ; diabetes ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes. Impaired glucose tolerance ; Diabetic Nephropathies - epidemiology ; Diabetic Retinopathy - epidemiology ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Etiopathogenesis. Screening. Investigations. Target tissue resistance ; Feeding. Feeding behavior ; Female ; Fundamental and applied biological sciences. Psychology ; Glucose Tolerance Test - methods ; Humans ; India - epidemiology ; Male ; Medical sciences ; Middle Aged ; neuropathy ; Prevalence ; Risk Factors ; Rural Health - statistics & numerical data ; Urban Health - statistics & numerical data ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; Vertebrates: endocrinology</subject><ispartof>Diabetic medicine, 2008-04, Vol.25 (4), p.407-412</ispartof><rights>2008 The Authors</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4667-4654c7c9696029d4b71f884a01ef6b42e74375c3b11df33b87c04d8f1c0c77b53</citedby><cites>FETCH-LOGICAL-c4667-4654c7c9696029d4b71f884a01ef6b42e74375c3b11df33b87c04d8f1c0c77b53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20290696$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18294224$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pradeepa, R.</creatorcontrib><creatorcontrib>Rema, M.</creatorcontrib><creatorcontrib>Vignesh, J.</creatorcontrib><creatorcontrib>Deepa, M.</creatorcontrib><creatorcontrib>Deepa, R.</creatorcontrib><creatorcontrib>Mohan, V.</creatorcontrib><title>Prevalence and risk factors for diabetic neuropathy in an urban south Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55)</title><title>Diabetic medicine</title><addtitle>Diabet Med</addtitle><description>Aims This study was conducted to determine the prevalence of, and risk factors for, diabetic neuropathy (DN) in south Indian Type 2 diabetic subjects.
Methods Subjects were recruited from the Chennai Urban Rural Epidemiology Study, conducted on a representative cohort from Chennai city. A total of 1629 diabetic subjects were included, of whom 1291 were known to have diabetes (KD) subjects and 338 were randomly selected newly detected diabetic (NDD) subjects. Neuropathy was diagnosed if vibratory perception threshold at the great toe, measured by biothesiometry, exceeded mean + 2 sd of a healthy non‐diabetic study population aged 20–45 years (cut point ≥ 20 V).
Results The overall prevalence of DN was 26.1% (age‐adjusted 13.1%) with no significant difference in gender. The prevalence of neuropathy was significantly higher in KD subjects compared with NDD subjects (27.8 vs. 19.5%, P = 0.002). The prevalence of diabetic retinopathy (24.1 vs. 15.3%, P < 0.0001) and hypertension (51.1 vs. 40.0%, P < 0.0001) were higher in those with neuropathy compared with those without. The odds ratio for neuropathy in subjects with duration of diabetes > 15 years compared with ≤ 5 years was 5.7 (95% confidence interval: 3.52–9.08, P < 0.0001). Regression analysis showed age (P < 0.0001), glycated haemoglobin (P = 0.001) and duration of diabetes (P = 0.045) to be significantly associated with neuropathy.
Conclusions This cross‐sectional population‐based study shows that, among urban south Indian Type 2 diabetic subjects, the prevalence of DN is 26.1% and that DN is significantly associated with age, glycated haemoglobin and duration of diabetes.</description><subject>Asian Indians</subject><subject>Biological and medical sciences</subject><subject>Body Composition</subject><subject>Cohort Studies</subject><subject>diabetes</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Diabetes. Impaired glucose tolerance</subject><subject>Diabetic Nephropathies - epidemiology</subject><subject>Diabetic Retinopathy - epidemiology</subject><subject>Endocrine pancreas. Apud cells (diseases)</subject><subject>Endocrinopathies</subject><subject>Etiopathogenesis. Screening. Investigations. Target tissue resistance</subject><subject>Feeding. Feeding behavior</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Glucose Tolerance Test - methods</subject><subject>Humans</subject><subject>India - epidemiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>neuropathy</subject><subject>Prevalence</subject><subject>Risk Factors</subject><subject>Rural Health - statistics & numerical data</subject><subject>Urban Health - statistics & numerical data</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>Vertebrates: endocrinology</subject><issn>0742-3071</issn><issn>1464-5491</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNqNkdFu0zAUhi0EYmXwCsg3IHaRYDuOnSBxAaWMiQ1Qt4pLy3Ec6i61MzuB5iV4Zpy1KpfgC9uSv__46HwAQIxSHNfrTYopo0lOS5wShIoUkazk6e4BmB0fHoIZ4pQkGeL4BDwJYYMQJmVWPgYnuCAlJYTOwO9vXv-UrbZKQ2lr6E24hY1UvfMBNs7D2shK90ZBqwfvOtmvR2hsZOHgq7gHN_RreGEjZ2HnuqGVvXH2DezXGs7X2lpp4OoeXQ5etnDRmVpvjWvdjxFe90M9wlfz1XJxneT52VPwqJFt0M8O5ylYfVzczD8ll1_PL-bvLhNFGeMJZTlVXJWsZIiUNa04boqCSoR1wypKNKcZz1VWYVw3WVYVXCFaFw1WSHFe5dkpeLmv23l3N-jQi60JSrettNoNQXBEY-2C_xMkiJWEYRTBYg8q70LwuhGdN1vpR4GRmKSJjZjciMmNmKSJe2liF6PPD38M1VbXf4MHSxF4cQBkULJtvLTKhCNH4gxiGyxyb_fcL9Pq8b8bEB-uFtMt5pN93oRe74556W8F43Gg4vuXc_H-6vPyZp4hscz-AInrwWw</recordid><startdate>200804</startdate><enddate>200804</enddate><creator>Pradeepa, R.</creator><creator>Rema, M.</creator><creator>Vignesh, J.</creator><creator>Deepa, M.</creator><creator>Deepa, R.</creator><creator>Mohan, V.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>200804</creationdate><title>Prevalence and risk factors for diabetic neuropathy in an urban south Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55)</title><author>Pradeepa, R. ; Rema, M. ; Vignesh, J. ; Deepa, M. ; Deepa, R. ; Mohan, V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4667-4654c7c9696029d4b71f884a01ef6b42e74375c3b11df33b87c04d8f1c0c77b53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Asian Indians</topic><topic>Biological and medical sciences</topic><topic>Body Composition</topic><topic>Cohort Studies</topic><topic>diabetes</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Diabetes. Impaired glucose tolerance</topic><topic>Diabetic Nephropathies - epidemiology</topic><topic>Diabetic Retinopathy - epidemiology</topic><topic>Endocrine pancreas. Apud cells (diseases)</topic><topic>Endocrinopathies</topic><topic>Etiopathogenesis. Screening. Investigations. Target tissue resistance</topic><topic>Feeding. Feeding behavior</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Glucose Tolerance Test - methods</topic><topic>Humans</topic><topic>India - epidemiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>neuropathy</topic><topic>Prevalence</topic><topic>Risk Factors</topic><topic>Rural Health - statistics & numerical data</topic><topic>Urban Health - statistics & numerical data</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><topic>Vertebrates: endocrinology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pradeepa, R.</creatorcontrib><creatorcontrib>Rema, M.</creatorcontrib><creatorcontrib>Vignesh, J.</creatorcontrib><creatorcontrib>Deepa, M.</creatorcontrib><creatorcontrib>Deepa, R.</creatorcontrib><creatorcontrib>Mohan, V.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Diabetic medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pradeepa, R.</au><au>Rema, M.</au><au>Vignesh, J.</au><au>Deepa, M.</au><au>Deepa, R.</au><au>Mohan, V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence and risk factors for diabetic neuropathy in an urban south Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55)</atitle><jtitle>Diabetic medicine</jtitle><addtitle>Diabet Med</addtitle><date>2008-04</date><risdate>2008</risdate><volume>25</volume><issue>4</issue><spage>407</spage><epage>412</epage><pages>407-412</pages><issn>0742-3071</issn><eissn>1464-5491</eissn><coden>DIMEEV</coden><abstract>Aims This study was conducted to determine the prevalence of, and risk factors for, diabetic neuropathy (DN) in south Indian Type 2 diabetic subjects.
Methods Subjects were recruited from the Chennai Urban Rural Epidemiology Study, conducted on a representative cohort from Chennai city. A total of 1629 diabetic subjects were included, of whom 1291 were known to have diabetes (KD) subjects and 338 were randomly selected newly detected diabetic (NDD) subjects. Neuropathy was diagnosed if vibratory perception threshold at the great toe, measured by biothesiometry, exceeded mean + 2 sd of a healthy non‐diabetic study population aged 20–45 years (cut point ≥ 20 V).
Results The overall prevalence of DN was 26.1% (age‐adjusted 13.1%) with no significant difference in gender. The prevalence of neuropathy was significantly higher in KD subjects compared with NDD subjects (27.8 vs. 19.5%, P = 0.002). The prevalence of diabetic retinopathy (24.1 vs. 15.3%, P < 0.0001) and hypertension (51.1 vs. 40.0%, P < 0.0001) were higher in those with neuropathy compared with those without. The odds ratio for neuropathy in subjects with duration of diabetes > 15 years compared with ≤ 5 years was 5.7 (95% confidence interval: 3.52–9.08, P < 0.0001). Regression analysis showed age (P < 0.0001), glycated haemoglobin (P = 0.001) and duration of diabetes (P = 0.045) to be significantly associated with neuropathy.
Conclusions This cross‐sectional population‐based study shows that, among urban south Indian Type 2 diabetic subjects, the prevalence of DN is 26.1% and that DN is significantly associated with age, glycated haemoglobin and duration of diabetes.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>18294224</pmid><doi>10.1111/j.1464-5491.2008.02397.x</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0742-3071 |
| ispartof | Diabetic medicine, 2008-04, Vol.25 (4), p.407-412 |
| issn | 0742-3071 1464-5491 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70469687 |
| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Asian Indians Biological and medical sciences Body Composition Cohort Studies diabetes Diabetes Mellitus, Type 2 - epidemiology Diabetes. Impaired glucose tolerance Diabetic Nephropathies - epidemiology Diabetic Retinopathy - epidemiology Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Glucose Tolerance Test - methods Humans India - epidemiology Male Medical sciences Middle Aged neuropathy Prevalence Risk Factors Rural Health - statistics & numerical data Urban Health - statistics & numerical data Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology |
| title | Prevalence and risk factors for diabetic neuropathy in an urban south Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55) |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T06%3A59%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevalence%20and%20risk%20factors%20for%20diabetic%20neuropathy%20in%20an%20urban%20south%20Indian%20population:%20the%20Chennai%20Urban%20Rural%20Epidemiology%20Study%20(CURES-55)&rft.jtitle=Diabetic%20medicine&rft.au=Pradeepa,%20R.&rft.date=2008-04&rft.volume=25&rft.issue=4&rft.spage=407&rft.epage=412&rft.pages=407-412&rft.issn=0742-3071&rft.eissn=1464-5491&rft.coden=DIMEEV&rft_id=info:doi/10.1111/j.1464-5491.2008.02397.x&rft_dat=%3Cproquest_cross%3E70469687%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c4667-4654c7c9696029d4b71f884a01ef6b42e74375c3b11df33b87c04d8f1c0c77b53%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=20692610&rft_id=info:pmid/18294224&rfr_iscdi=true |