Comparison of Prevalence of Varicocele in First-Degree Relatives of Patients with Varicocele and Male Kidney Donors

Objectives To evaluate hereditary behavior of varicocele through comparison of prevalence of disease in first-degree relatives of patients with known varicocele and normal healthy kidney donation volunteers. Methods Sixty-two patients with known varicocele who admitted for surgery in Razi Hospital b...

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Published in:Urology (Ridgewood, N.J.) N.J.), 2008-04, Vol.71 (4), p.666-668
Main Authors: Mokhtari, Gholamreza, Pourreza, Farshid, Falahatkar, Siavash, Kamran, Alireza Noshad, Jamali, Maryam
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Case-Control Studies
Cohort Studies
Genetic Predisposition to Disease - genetics
Gynecology. Andrology. Obstetrics
Humans
Inheritance Patterns
Iran
Kidney Transplantation
Male
Male genital diseases
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Non tumoral diseases
Prevalence
Tissue Donors
Urology
Varicocele - epidemiology
Varicocele - genetics
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Summary:Objectives To evaluate hereditary behavior of varicocele through comparison of prevalence of disease in first-degree relatives of patients with known varicocele and normal healthy kidney donation volunteers. Methods Sixty-two patients with known varicocele who admitted for surgery in Razi Hospital between September 2005 and October 2006 were enrolled in the study. The patients were asked to refer for examination healthy available first-degree relatives (n = 88). A group of 100 men referred for voluntary kidney donation were selected as control group and assessed for varicocele. Results Of the 88 first-degree relatives of patients with a known varicocele, 40 (45.4%) had a clinically palpable varicocele on physical examination. This was significantly greater than the 11 (11%) of 100 men in the control group ( P
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2007.11.116