The influence of corticosteroids on the perception of dyspnea in asthma

Summary Corticosteroids are effective anti-inflammatory medications that are recommended for the control of persistent asthma. Little, however, is known about their influence on the perception of dyspnea, which, in turn, is important to the successful self-management of asthma. This paper provides a...

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Bibliographic Details
Published in:Respiratory medicine 2007-06, Vol.101 (6), p.1079-1087
Main Authors: von Leupoldt, Andreas, Kanniess, Frank, Dahme, Bernhard
Format: Article
Language:English
Subjects:
Anti-Inflammatory Agents - therapeutic use
Asthma
Asthma - complications
Asthma - drug therapy
Asthma - psychology
Biological and medical sciences
Biomedical Research
Bone density
Bones, joints and connective tissue. Antiinflammatory agents
Breathlessness
Chronic obstructive pulmonary disease, asthma
Corticosteroid
Drug therapy
Dyspnea
Dyspnea - drug therapy
Dyspnea - etiology
Dyspnea - psychology
Glucocorticoids - therapeutic use
Humans
Inflammation
Influence
Lead
Medical sciences
Perception
Perception - drug effects
Pharmacology. Drug treatments
Pneumology
Pulmonary/Respiratory
Respiratory system : syndromes and miscellaneous diseases
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Summary:Summary Corticosteroids are effective anti-inflammatory medications that are recommended for the control of persistent asthma. Little, however, is known about their influence on the perception of dyspnea, which, in turn, is important to the successful self-management of asthma. This paper provides a synopsis of available studies examining the impact of corticosteroids on the sensitivity to perceive dyspnea and presents possible mechanisms underlying this relationship. The results of these investigations are conflicting with some studies showing improved perception and other studies showing worsened perception of dyspnea after corticosteroid treatment. Thus, firm conclusions cannot be derived from the currently available data. Implications for future research, which is required to increase our understanding of potential influences of corticosteroids on the perception of dyspnea, are provided.
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2006.10.026