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Outcome of non-invasive domiciliary ventilation in elderly patients

Summary Study objectives To analyze the short- and long-term effects of domiciliary non-invasive ventilation (NIV) in the elderly. Methods From 1990 to 2005 all patients who initiated NIV at age 75 or older were included in the study. The mean follow-up period was 36 (24) months. Data were obtained...

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Bibliographic Details
Published in:Respiratory medicine 2007-06, Vol.101 (6), p.1068-1073
Main Authors: Farrero, Eva, Prats, Enric, Manresa, Frederic, Escarrabill, Joan
Format: Article
Language:English
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Summary:Summary Study objectives To analyze the short- and long-term effects of domiciliary non-invasive ventilation (NIV) in the elderly. Methods From 1990 to 2005 all patients who initiated NIV at age 75 or older were included in the study. The mean follow-up period was 36 (24) months. Data were obtained from a database record. Results Forty-three patients, mean age 77 (1.9) years and hypercapnic respiratory failure secondary to restrictive, neuromuscular or hypoventilatory disease were included. The short-term effects included a significant improvement in arterial blood gases and nocturnal desaturations during NIV compared to baseline: P aO2 increased a mean of 19 mmHg ( P < 0.0001 ) , P aCO2 decreased a mean of 16 mmHg ( P < 0.0001 ) and nocturnal time with S aO2
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2006.10.005