Fresh frozen plasma transfusion for reversal of prolonged post‐anaesthesia apnoea

summary An 18‐year old woman admitted for tonsillectomy developed prolonged post‐operative paralysis after anaesthesia with mivacurium. Investigation revealed a decreased cholinesterase activity because of a homozygous atypical and heterozygous K variant of the cholinesterase gene. Transfusion of fr...

Full description

Saved in:
Bibliographic Details
Published in:Transfusion medicine (Oxford, England) England), 2008-04, Vol.18 (2), p.134-136
Main Authors: Van Gammeren, A. J., Cobbaert, C. M., Schrauwen, C. J. M., Voets, M. A. J., Ermens, A. A. M.
Format: Article
Language:English
Subjects:
Adolescent
Apnea - etiology
Apnea - therapy
Blood Transfusion - methods
cholinesterase deficiency
Female
FFP transfusion
fresh frozen plasma
Humans
mivacurium
Paralysis - etiology
Plasma
Postoperative Complications - therapy
prolonged apnoea
Tonsillectomy - adverse effects
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:summary An 18‐year old woman admitted for tonsillectomy developed prolonged post‐operative paralysis after anaesthesia with mivacurium. Investigation revealed a decreased cholinesterase activity because of a homozygous atypical and heterozygous K variant of the cholinesterase gene. Transfusion of fresh frozen plasma was associated with reversal of the respiratory paralysis and complete recovery.
ISSN:0958-7578
1365-3148
DOI:10.1111/j.1365-3148.2008.00851.x