Ethnicity and Nonalcoholic Fatty Liver Disease in an Obesity Clinic: The Impact of Triglycerides

Nonalcoholic fatty liver disease (NAFLD) is a growing problem that is associated with the metabolic syndrome. The goal of the present study was to evaluate for ethnic differences in NAFLD and clinical correlates of NAFLD. The study population consisted of 567 patients seen at an urban obesity clinic...

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Bibliographic Details
Published in:Digestive diseases and sciences 2008-05, Vol.53 (5), p.1358-1363
Main Authors: Kallwitz, Eric R., Kumar, Mrudula, Aggarwal, Radhika, Berger, Reed, Layden-Almer, Jennifer, Gupta, Neil, Cotler, Scott J.
Format: Article
Language:English
Subjects:
Adult
Alanine Transaminase - blood
Analysis of Variance
Biochemistry
Biological and medical sciences
Chicago - epidemiology
Fatty Liver - epidemiology
Fatty Liver - ethnology
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Gastroenterology
Gastroenterology. Liver. Pancreas. Abdomen
Hepatology
Humans
Hypertriglyceridemia - epidemiology
Hypertriglyceridemia - ethnology
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Medicine
Medicine & Public Health
Metabolic diseases
Obesity
Obesity - epidemiology
Obesity - ethnology
Oncology
Original Paper
Other diseases. Semiology
Prevalence
Retrospective Studies
Risk Factors
Transplant Surgery
Urban Population
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Summary:Nonalcoholic fatty liver disease (NAFLD) is a growing problem that is associated with the metabolic syndrome. The goal of the present study was to evaluate for ethnic differences in NAFLD and clinical correlates of NAFLD. The study population consisted of 567 patients seen at an urban obesity clinic. Elevated aminotransferase levels were used as a surrogate marker for NAFLD. The prevalence of elevated aminotransferases was highest in Hispanics (39%), followed by Caucasians (28%), and African Americans (12%). In univariate analysis, elevated aminotransferase levels were associated with ethnicity (Hispanic > African American, P   African American P  = 0.030), hypertriglyceridemia ( P  
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-008-0234-x