Appendicitis in immunosuppressed children: Still a diagnostic and therapeutic dilemma?

Acute appendicitis in the immunosuppressed patients are often difficult to diagnose and are associated with increased morbidity and mortality. Recent debates on primary appendicitis and typhlitis‐associated appendicitis have contributed to the diagnostic and therapeutic dilemma. We retrospectively r...

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Bibliographic Details
Published in:Pediatric Blood & Cancer 2008-06, Vol.50 (6), p.1282-1283
Main Authors: Chui, Chan-Hon, Chan, Mei-Yoke, Tan, Ah-Moy, Low, Yee, Yap, Te-Lu, Jacobsen, Anette S.
Format: Article
Language:English
Subjects:
Adolescent
Appendectomy
appendicitis
Appendicitis - diagnosis
Appendicitis - surgery
Child
Child, Preschool
children
Diagnosis, Differential
Female
Humans
immunosuppressed
Immunosuppression
Male
neutropenic colitis
typhlitis
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Summary:Acute appendicitis in the immunosuppressed patients are often difficult to diagnose and are associated with increased morbidity and mortality. Recent debates on primary appendicitis and typhlitis‐associated appendicitis have contributed to the diagnostic and therapeutic dilemma. We retrospectively reviewed all our immunosuppressed patients with appendicitis. The most frequent presenting symptom was fever followed by non‐specific intermittent abdominal pain. The median delay in diagnosis was 4 days. CT scan was useful in making the diagnosis, but the presence of adjacent bowel thickening has contributed to the dilemma in diagnosis and treatment. Pediatr Blood Cancer 2008;50:1282–1283. © 2008 Wiley‐Liss, Inc.
ISSN:1545-5009
1545-5017
1096-911X
DOI:10.1002/pbc.21554