Wilms tumour in Sudan

Background Wilms tumour is one of the commonest childhood solid tumours which has an excellent outlook in the developed world with 5‐year overall survival exceeding 90%. There is little information from Sudan regarding Wilms tumour. Procedure Records of patients with Wilms tumour diagnosed and treat...

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Published in:Pediatric blood & cancer 2008-06, Vol.50 (6), p.1135-1137
Main Authors: Abuidris, Dafalla O., Elimam, Mohammed E., Nugud, Faisal M., Elgaili, Elgaili M., Ahmed, Mohamed E., Arora, Ramandeep S.
Format: Article
Language:English
Subjects:
abandonment
Adolescent
Africa
Child
Child, Preschool
Developing Countries
developing country
Female
Humans
Infant
Kidney Neoplasms - diagnosis
Kidney Neoplasms - epidemiology
Kidney Neoplasms - therapy
Male
outcomes
Sudan
Sudan - epidemiology
Wilms Tumor - diagnosis
Wilms Tumor - epidemiology
Wilms Tumor - therapy
Wilms tumour
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Summary:Background Wilms tumour is one of the commonest childhood solid tumours which has an excellent outlook in the developed world with 5‐year overall survival exceeding 90%. There is little information from Sudan regarding Wilms tumour. Procedure Records of patients with Wilms tumour diagnosed and treated at Institute of Nuclear Medicine, Molecular Biology and Oncology (INMO) in the University of Gezira from May 1999 to June 2007 were reviewed. Results Thirty‐seven children presented at a mean age of 4.1 years (range 2 months–13 years). The male to female ratio was 0.9–1. Abdominal swelling or mass was the commonest symptom. There was 1 child with Stage I (2.7%), 7 with stage II (18.9%), 25 with Stage III (67.6%) and 4 with Stage IV (10.8%). Following diagnosis 27% of children did not receive further treatment (5.4% died prior to treatment, 5.4% were not able to finance treatment and for the rest 16.2% no cause was identified). More than half of the children did not have a nephrectomy and only 4 (11%) completed treatment. Conclusions The poor outlook is related to several factors. Delayed presentation, poor awareness of treatment options, lack of finances, no provision of food, lodging and transport, absence of paediatric trained staff are the obstacles to better outcomes. Empowering parents with information, giving chemotherapy prior to nephrectomy, training staff and establishing links with a tertiary cancer centre in the developed world are some of the options to improve survival. Pediatr Blood Cancer 2008;50:1135–1137. © 2008 Wiley‐Liss, Inc.
ISSN:1545-5009
1545-5017
DOI:10.1002/pbc.21547