HMG-box sequences from microbats homologous to the human SOX30 HMG-box

SOX genes are a family of genes that encode for proteins which are characterised by the presence of a HMG-domain related to that of the mammalian sex-determining gene (SRY). By definition, the DNA binding domain of SOX genes is at least 50% identical to the 79 amino acid HMG domain of the SRY gene....

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Bibliographic Details
Published in:Genetica 2000-01, Vol.110 (2), p.157-162
Main Authors: Bullejos, M, Díaz de la Guardia, R, Barragán, M J, Sánchez, A
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Amino acids
Animals
Base Sequence
Bats
Chiroptera - genetics
DNA - genetics
DNA Primers - genetics
DNA-Binding Proteins - genetics
Female
Genes, sry
high mobility group box
High Mobility Group Proteins - genetics
HMG-Box Domains - genetics
Humans
Male
Mice
Molecular Sequence Data
Pipistrellus pipistrellus
Rhinolophus ferrumequinum
Sequence Homology, Amino Acid
Sequence Homology, Nucleic Acid
SOX gene
SOX30 gene
SOXB2 Transcription Factors
Species Specificity
SRY gene
Zebrafish Proteins
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Summary:SOX genes are a family of genes that encode for proteins which are characterised by the presence of a HMG-domain related to that of the mammalian sex-determining gene (SRY). By definition, the DNA binding domain of SOX genes is at least 50% identical to the 79 amino acid HMG domain of the SRY gene. We report here two HMG-box sequences from two microbat species (R. ferrumequinum and P. Pipistrellus) which were PCR amplified using a primer pair specific to the mouse Sry HMG-box. The high percentage of identity of this sequences with the human and mouse SOX30 HMG-box suggests that they are the SOX30 HMG-box for these two bat species.
ISSN:0016-6707
1573-6857
DOI:10.1023/A:1017914005677