Detecting Breast Cancer with Non-contrast MR Imaging: Combining Diffusion-weighted and STIR Imaging

We combined diffusion-weighted (DWI) and short TI inversion recovery (STIR) imaging to evaluate the diagnostic capability of non-contrast magnetic resonance (MR) imaging to detect breast cancer. Seventy women patients underwent mammography and MR imaging with combined DWI (b factor: 1000) and STIR t...

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Bibliographic Details
Published in:Magnetic Resonance in Medical Sciences 2007, Vol.6(1), pp.21-27
Main Authors: KUROKI-SUZUKI, Seiko, KUROKI, Yoshifumi, NASU, Katsuhiro, NAWANO, Shigeru, MORIYAMA, Noriyuki, OKAZAKI, Masatoshi
Format: Article
Language:English
Subjects:
Adult
Aged
breast cancer
Breast Neoplasms - diagnosis
Carcinoma - diagnosis
Contrast Media
Diffusion Magnetic Resonance Imaging - methods
diffusion-weighted image (DWI)
Humans
Image Enhancement - methods
Image Interpretation, Computer-Assisted - methods
Middle Aged
MRI
STIR
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Summary:We combined diffusion-weighted (DWI) and short TI inversion recovery (STIR) imaging to evaluate the diagnostic capability of non-contrast magnetic resonance (MR) imaging to detect breast cancer. Seventy women patients underwent mammography and MR imaging with combined DWI (b factor: 1000) and STIR that revealed malignancy, and postoperative pathological examination confirmed breast cancer. Interpreted images were evaluated for sensitivity, false negative rate (FN), sensitivity by pT, and sensitivity by background density of the mammary gland. Of the 70 cases, 68 were diagnosed as cancer by DWI and STIR (sensitivity, 97% [68/70]; FN, 2.9% [2/70]). Sensitivities by pT were: pTis, 67% (4/6); pT1, 100% (33/33); and pT2-4, 100% (31/31). No significant differences were observed in sensitivity between pT1 and pT2-4 (P
ISSN:1347-3182
1880-2206
DOI:10.2463/mrms.6.21