Endometrial carcinoma first presenting as paraneoplastic cerebellar degeneration

Abstract Background. Paraneoplastic degeneration (PCD) is an immune-mediated disorder affecting the cerebellum, characterized by subacute onset of cerebellar dysfunction progressing to severe disability, and is associated with an underlying malignancy. Ovarian carcinoma and breast carcinoma are comm...

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Published in:Gynecologic oncology 2007-06, Vol.105 (3), p.826-827
Main Authors: Erez, Yair, Rojansky, Nathan, Shveiky, David, Ben-Meir, Assaf, Benshushan, Avi
Format: Article
Language:English
Subjects:
Aged
Anti-YO
Endometrial carcinoma
Endometrial Neoplasms - diagnosis
Endometrial Neoplasms - immunology
Female
Hematology, Oncology and Palliative Medicine
Humans
Obstetrics and Gynecology
Paraneoplastic Cerebellar Degeneration - diagnosis
Paraneoplastic Cerebellar Degeneration - immunology
Paraneoplastic degeneration
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creator Erez, Yair
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description Abstract Background. Paraneoplastic degeneration (PCD) is an immune-mediated disorder affecting the cerebellum, characterized by subacute onset of cerebellar dysfunction progressing to severe disability, and is associated with an underlying malignancy. Ovarian carcinoma and breast carcinoma are commonly implicated. Case. We report a rare case PCD in an elderly woman, later diagnosed with endometrial carcinoma. Conclusion. PCD is an unusual and rare manifestation of gynecological malignancies, including endometrial carcinoma, and a high degree of suspicion is required in these cases in order to make the correct diagnosis.
doi_str_mv 10.1016/j.ygyno.2007.02.023
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subjects Aged
Anti-YO
Endometrial carcinoma
Endometrial Neoplasms - diagnosis
Endometrial Neoplasms - immunology
Female
Hematology, Oncology and Palliative Medicine
Humans
Obstetrics and Gynecology
Paraneoplastic Cerebellar Degeneration - diagnosis
Paraneoplastic Cerebellar Degeneration - immunology
Paraneoplastic degeneration
title Endometrial carcinoma first presenting as paraneoplastic cerebellar degeneration
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