Association of n-3 and n-6 long-chain polyunsaturated fatty acids in plasma lipid classes with inflammatory bowel diseases

In order to establish the biochemical basis for dietary interventions, we investigated the fatty acid composition of plasma lipid classes in patients with inactive inflammatory bowel disease. In this cross-sectional study thirty patients with ulcerative colitis (UC), twenty-one with Crohn disease (C...

Full description

Saved in:
Bibliographic Details
Published in:British journal of nutrition 2007-06, Vol.97 (6), p.1154-1161
Main Authors: Figler, Mária, Gasztonyi, Beata, Cseh, Judit, Horváth, Gábor, Kisbenedek, Andrea G., Bokor, Szilvia, Decsi, Tamás
Format: Article
Language:English
Subjects:
Adult
adults
Arachidonic acid
Biological and medical sciences
Biomarkers - blood
blood lipids
Cholesterol
colitis
Colitis, Ulcerative - blood
Composition
Crohn disease
Crohn Disease - blood
Cross-Sectional Studies
Diet
Disease
Disease control
docosahexaenoic acid
docosapentaenoic acid
docosenoic acids
Eicosapentaenoic acid
Fatty acid composition
Fatty acids
Fatty Acids, Omega-3 - blood
Fatty Acids, Omega-6 - blood
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
gamma-linolenic acid
Humans
Inflammatory bowel disease
Inflammatory bowel diseases
Inflammatory Bowel Diseases - blood
Intestine
Investigations
Lipids
Male
Malnutrition
Middle Aged
omega-3 fatty acids
omega-6 fatty acids
patients
Phospholipids
Phospholipids - blood
Plasma
Polyunsaturated fatty acids
Proteins
Standard deviation
Sterols
Triglycerides - blood
Ulcerative colitis
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Weight
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In order to establish the biochemical basis for dietary interventions, we investigated the fatty acid composition of plasma lipid classes in patients with inactive inflammatory bowel disease. In this cross-sectional study thirty patients with ulcerative colitis (UC), twenty-one with Crohn disease (CD) and twenty-four controls were investigated (mean age: UC, 40·8 (sd 12·1); CD, 37·6 (sd 11·0); control, 31·5 (sd 8·4) years). Fatty acid composition of plasma lipids was determined by high-resolution capillary GLC. In plasma phospholipids, significantly higher values of eicosapentaenoic (20 : 5n-3), docosapentaenoic (22 : 5n-3) and γ-linolenic (18 : 3n-6) acids were found in control patients and patients with UC as compared to patients with CD [median % (weight by weight), control v. UC v. CD : 20 : 5n-3, 0·09 (interquartile range (IQR) 0·05) v. 0·14 (IQR 0·10) v. 0·16 (IQR 0·10), P 
ISSN:0007-1145
1475-2662
DOI:10.1017/S0007114507682956