Prediction of Inpatient Survival and Graft Loss in Rehospitalized Kidney Recipients

• Published in: Transplantation proceedings 2007-05, Vol.39 (4), p.974-977
• Main Authors: Nemati, E, Pourfarziani, V, Jafari, A.M, Assari, S, Moghani-Lankarani, M, Khedmat, H, Bagheri, N, Saadat, S.H
• Format: Article
• Language: English
• Subjects: Adult; Biological and medical sciences; Female; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Graft Survival - physiology; Hospital Mortality; Humans; Inpatients - statistics & numerical data; Iran; Kidney Transplantation - mortality; Kidney Transplantation - physiology; Length of Stay; Male; Medical sciences; Middle Aged; Patient Readmission - statistics & numerical data; Retrospective Studies; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Survival Analysis; Tissue, organ and graft immunology
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2007.03.093

Abstract Introduction Despite a sizeable amount of research conducted hitherto into predictors of renal transplantation outcomes, there are scarce, data on predictors of in-hospital outcomes of post–kidney transplant rehospitalization. This study sought to provide a user-friendly prediction model for inpatient mortality and graft loss among rehospitalized kidney recipients. Method This retrospective review of 424 consecutive kidney recipients rehospitalized after kidney transplantation between the years 2000 and 2005 used multiple logistic regression analysis to evaluate predictors of hospitalization outcomes. Results Multivariate analysis showed that age at admission, diabetes mellitus as the cause of end-stage renal disease (ESRD), admission due to cerebrovascular accident (CVA), surgical complications were predictors of in-hospital death; age at transplantation, surgical complications, and rejection were predictors of graft loss. Equation for prediction of in-hospital death was Logit(death) −0.304 * age at transplantation (year) + 0.284 ⁎ age at admission (year) + 1.621 ⁎ admission for surgical complication + 4.001 ⁎ admission for CVA-ischemic heart disease + 2.312 ⁎ diabetes as cause of ESRD. Equation for prediction of in-hospital death was Logit(graft loss) = 0.041 ⁎ age at transplantation (year) + 1.184 ⁎ admission for graft rejection + 1.798 ⁎ admission for surgical complication. Conclusions Our prediction equations, using simple demographic and clinical variables, estimated the probability of inpatient mortality and graft loss among re-hospitalized kidney recipients.